Modern Radiotherapy and Cardiac Toxicity in Breast Cancer
Radiotherapy (RT) is a mainstay of Breast Cancer (BC) patients therapy. Nonetheless, unintended irradiation of the heart and its substructures can result in cardiac toxicity, jeopardizing long-term survivors’ quality of life (QOL). Advances in RT delivery techniques deeply impacted this clinical sce...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2023-07-01
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| Series: | Clinical and Experimental Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/CEOG/50/7/10.31083/j.ceog5007138 |
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| Summary: | Radiotherapy (RT) is a mainstay of Breast Cancer (BC) patients therapy. Nonetheless, unintended irradiation of the heart and its substructures can result in cardiac toxicity, jeopardizing long-term survivors’ quality of life (QOL). Advances in RT delivery techniques deeply impacted this clinical scenario. Indeed, given the non-negligible burden of cardiotoxicity, modern cardiac sparing approaches have a pivotal role. Nonetheless, further evidence is eagerly awaited regarding patients’ selection, clinical predictors, biological markers, and particularly heart substructures dose-constraints. |
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| ISSN: | 0390-6663 |