Advances in the application of platelet-rich plasma in peripheral nerve injuries

Abstract Peripheral nerve injury (PNI) can occur after various types of trauma; these are common clinical injuries. These injuries often result in chronic conditions such as neuropathic pain and permanent disabilities, severely affecting quality of life and work. Achieving optimal repair of injured...

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Main Authors: Xiao-Yu Dou, Min An
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Anesthesiology and Perioperative Science
Subjects:
Online Access:https://doi.org/10.1007/s44254-025-00100-x
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author Xiao-Yu Dou
Min An
author_facet Xiao-Yu Dou
Min An
author_sort Xiao-Yu Dou
collection DOAJ
description Abstract Peripheral nerve injury (PNI) can occur after various types of trauma; these are common clinical injuries. These injuries often result in chronic conditions such as neuropathic pain and permanent disabilities, severely affecting quality of life and work. Achieving optimal repair of injured peripheral nerves remains a focal point of clinical research. In recent years, platelet-rich plasma (PRP) has been increasingly applied in clinical settings due to associated high concentration of various growth factors that promote tissue repair. Here we review advances in PNI repair and the prospect of using autologous PRP as a treatment paradigm.
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issn 2731-8389
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publishDate 2025-04-01
publisher Springer
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series Anesthesiology and Perioperative Science
spelling doaj-art-e1ccd7313a564c0f88d0fe6953bff7662025-08-20T03:18:39ZengSpringerAnesthesiology and Perioperative Science2731-83892025-04-01321910.1007/s44254-025-00100-xAdvances in the application of platelet-rich plasma in peripheral nerve injuriesXiao-Yu Dou0Min An1Graduate School of Inner Mongolia Medical UniversityGraduate School of Inner Mongolia Medical UniversityAbstract Peripheral nerve injury (PNI) can occur after various types of trauma; these are common clinical injuries. These injuries often result in chronic conditions such as neuropathic pain and permanent disabilities, severely affecting quality of life and work. Achieving optimal repair of injured peripheral nerves remains a focal point of clinical research. In recent years, platelet-rich plasma (PRP) has been increasingly applied in clinical settings due to associated high concentration of various growth factors that promote tissue repair. Here we review advances in PNI repair and the prospect of using autologous PRP as a treatment paradigm.https://doi.org/10.1007/s44254-025-00100-xPlatelet-rich plasmaPeripheral nerve injuryChronic pain
spellingShingle Xiao-Yu Dou
Min An
Advances in the application of platelet-rich plasma in peripheral nerve injuries
Anesthesiology and Perioperative Science
Platelet-rich plasma
Peripheral nerve injury
Chronic pain
title Advances in the application of platelet-rich plasma in peripheral nerve injuries
title_full Advances in the application of platelet-rich plasma in peripheral nerve injuries
title_fullStr Advances in the application of platelet-rich plasma in peripheral nerve injuries
title_full_unstemmed Advances in the application of platelet-rich plasma in peripheral nerve injuries
title_short Advances in the application of platelet-rich plasma in peripheral nerve injuries
title_sort advances in the application of platelet rich plasma in peripheral nerve injuries
topic Platelet-rich plasma
Peripheral nerve injury
Chronic pain
url https://doi.org/10.1007/s44254-025-00100-x
work_keys_str_mv AT xiaoyudou advancesintheapplicationofplateletrichplasmainperipheralnerveinjuries
AT minan advancesintheapplicationofplateletrichplasmainperipheralnerveinjuries