Artificial intelligence in rheumatology research: what is it good for?

Artificial intelligence (AI) is transforming rheumatology research, with a myriad of studies aiming to improve diagnosis, prognosis and treatment prediction, while also showing potential capability to optimise the research workflow, improve drug discovery and clinical trials. Machine learning, a key...

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Main Authors: Diego Benavent, José Miguel Sequí-Sabater
Format: Article
Language:English
Published: BMJ Publishing Group 2025-01-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/11/1/e004309.full
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author Diego Benavent
José Miguel Sequí-Sabater
author_facet Diego Benavent
José Miguel Sequí-Sabater
author_sort Diego Benavent
collection DOAJ
description Artificial intelligence (AI) is transforming rheumatology research, with a myriad of studies aiming to improve diagnosis, prognosis and treatment prediction, while also showing potential capability to optimise the research workflow, improve drug discovery and clinical trials. Machine learning, a key element of discriminative AI, has demonstrated the ability of accurately classifying rheumatic diseases and predicting therapeutic outcomes by using diverse data types, including structured databases, imaging and text. In parallel, generative AI, driven by large language models, is becoming a powerful tool for optimising the research workflow by supporting with content generation, literature review automation and clinical decision support. This review explores the current applications and future potential of both discriminative and generative AI in rheumatology. It also highlights the challenges posed by these technologies, such as ethical concerns and the need for rigorous validation and regulatory oversight. The integration of AI in rheumatology promises substantial advancements but requires a balanced approach to optimise benefits and minimise potential possible downsides.
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spelling doaj-art-e1cc8abee78a4cb5a0175ffe5fb337ed2025-08-20T02:46:47ZengBMJ Publishing GroupRMD Open2056-59332025-01-0111110.1136/rmdopen-2024-004309Artificial intelligence in rheumatology research: what is it good for?Diego Benavent0José Miguel Sequí-Sabater1Rheumatology Department, Hospital Universitari de Bellvitge, L`Hospitalet de Llobregat, Barcelona, SpainRheumatology Department, La Ribera University Hospital, Alzira, SpainArtificial intelligence (AI) is transforming rheumatology research, with a myriad of studies aiming to improve diagnosis, prognosis and treatment prediction, while also showing potential capability to optimise the research workflow, improve drug discovery and clinical trials. Machine learning, a key element of discriminative AI, has demonstrated the ability of accurately classifying rheumatic diseases and predicting therapeutic outcomes by using diverse data types, including structured databases, imaging and text. In parallel, generative AI, driven by large language models, is becoming a powerful tool for optimising the research workflow by supporting with content generation, literature review automation and clinical decision support. This review explores the current applications and future potential of both discriminative and generative AI in rheumatology. It also highlights the challenges posed by these technologies, such as ethical concerns and the need for rigorous validation and regulatory oversight. The integration of AI in rheumatology promises substantial advancements but requires a balanced approach to optimise benefits and minimise potential possible downsides.https://rmdopen.bmj.com/content/11/1/e004309.full
spellingShingle Diego Benavent
José Miguel Sequí-Sabater
Artificial intelligence in rheumatology research: what is it good for?
RMD Open
title Artificial intelligence in rheumatology research: what is it good for?
title_full Artificial intelligence in rheumatology research: what is it good for?
title_fullStr Artificial intelligence in rheumatology research: what is it good for?
title_full_unstemmed Artificial intelligence in rheumatology research: what is it good for?
title_short Artificial intelligence in rheumatology research: what is it good for?
title_sort artificial intelligence in rheumatology research what is it good for
url https://rmdopen.bmj.com/content/11/1/e004309.full
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