Xiao’er Fengreqing oral liquid versus Xiao’er Yanbian granules for pediatric acute pharyngitis/tonsillitis (external wind heat syndrome): protocol and statistical analysis plan for a multi-center, randomized, double-blind, active drug-controlled trial

Xiao’er Fengreqing oral liquid versus Xiao’er Yanbian granules for pediatric acute pharyngitis/tonsillitis (external wind heat syndrome): protocol and statistical analysis plan for a multi-center, randomized, double-blind, active drug-controlled trial

ObjectiveTo evaluate the effectiveness and safety of Xiao’er Fengreqing Oral Liquid (XFOL) for pediatric acute pharyngitis/tonsillitis (external wind heat syndrome) through a multi-center, randomized, double-blind, positive-controlled, non-inferiority clinical trial.MethodA total of 120 participants...

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Bibliographic Details
Main Authors: Kai Liu, Lei Shi, Yi-Ke Song, Yu Du, Yi Yuan, Ze-Yang Shi, Jian-Ping Liu, Hui-Lan Liu, Zhao-Lan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
pharyngitis
tonsillitis
Xiao’er Fengreqing oral Liquid
randomized controlled trial
non-inferiority design
trial protocol
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1625547/full
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