Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study
This work illustrates the modification of carbon paste electrode (CPE) by electropolymerization of Congo red. The poly(Congo red) modified CPE (Congo red/MCPE) was used to study the electrochemical behaviour of paracetamol (PA) by cyclic voltammetry. Compared to bare CPE, Congo red/MCPE exhibited...
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International Association of Physical Chemists (IAPC)
2025-07-01
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| Series: | Journal of Electrochemical Science and Engineering |
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| Online Access: | https://pub.iapchem.org/ojs/index.php/JESE/article/view/2640 |
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| author | Chethan Kuskur Bahaddurghatta Eshwaraswamy Kumara Swamy |
| author_facet | Chethan Kuskur Bahaddurghatta Eshwaraswamy Kumara Swamy |
| author_sort | Chethan Kuskur |
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This work illustrates the modification of carbon paste electrode (CPE) by electropolymerization of Congo red. The poly(Congo red) modified CPE (Congo red/MCPE) was used to study the electrochemical behaviour of paracetamol (PA) by cyclic voltammetry. Compared to bare CPE, Congo red/MCPE exhibited better electrocatalytic activity towards the oxidation of PA, with an enhanced oxidation peak current in phosphate buffer solution at neutral pH and a sweep rate of 100 mV s-1. The effect of analyte concentration changes at Congo red/MCPE was studied by varying the concentration of PA and the limit of detection was found to be 1.1 µM. The proposed approach was successfully applied to the simultaneous measurement of paracetamol and dopamine, with the modified electrode exhibiting relatively high sensitivity, selectivity, and stability. The applicability of the developed method to determine the drug in pharmaceutical samples (tablets) is also illustrated.
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| format | Article |
| id | doaj-art-e1b9735f2da9418fa690921ed7bf6125 |
| institution | Kabale University |
| issn | 1847-9286 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | Journal of Electrochemical Science and Engineering |
| spelling | doaj-art-e1b9735f2da9418fa690921ed7bf61252025-08-20T03:30:57ZengInternational Association of Physical Chemists (IAPC)Journal of Electrochemical Science and Engineering1847-92862025-07-0110.5599/jese.2640Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric studyChethan Kuskur0https://orcid.org/0009-0002-3824-963XBahaddurghatta Eshwaraswamy Kumara Swamy1https://orcid.org/0000-0002-2433-0739Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankargatta, Shimoga, Karnataka 577451, IndiaDepartment of PG Studies and Research in Industrial Chemistry Kuvempu University Shankaraghatta, 577451, Shimoga, Karnataka, INDIA This work illustrates the modification of carbon paste electrode (CPE) by electropolymerization of Congo red. The poly(Congo red) modified CPE (Congo red/MCPE) was used to study the electrochemical behaviour of paracetamol (PA) by cyclic voltammetry. Compared to bare CPE, Congo red/MCPE exhibited better electrocatalytic activity towards the oxidation of PA, with an enhanced oxidation peak current in phosphate buffer solution at neutral pH and a sweep rate of 100 mV s-1. The effect of analyte concentration changes at Congo red/MCPE was studied by varying the concentration of PA and the limit of detection was found to be 1.1 µM. The proposed approach was successfully applied to the simultaneous measurement of paracetamol and dopamine, with the modified electrode exhibiting relatively high sensitivity, selectivity, and stability. The applicability of the developed method to determine the drug in pharmaceutical samples (tablets) is also illustrated. https://pub.iapchem.org/ojs/index.php/JESE/article/view/2640Diazo dyeelectro-polymerizationacetaminophen medicinevoltammetry techniqueselectrochemical sensor |
| spellingShingle | Chethan Kuskur Bahaddurghatta Eshwaraswamy Kumara Swamy Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study Journal of Electrochemical Science and Engineering Diazo dye electro-polymerization acetaminophen medicine voltammetry techniques electrochemical sensor |
| title | Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study |
| title_full | Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study |
| title_fullStr | Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study |
| title_full_unstemmed | Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study |
| title_short | Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study |
| title_sort | electrochemical investigation of paracetamol at congo red modified carbon paste electrode a voltammetric study |
| topic | Diazo dye electro-polymerization acetaminophen medicine voltammetry techniques electrochemical sensor |
| url | https://pub.iapchem.org/ojs/index.php/JESE/article/view/2640 |
| work_keys_str_mv | AT chethankuskur electrochemicalinvestigationofparacetamolatcongoredmodifiedcarbonpasteelectrodeavoltammetricstudy AT bahaddurghattaeshwaraswamykumaraswamy electrochemicalinvestigationofparacetamolatcongoredmodifiedcarbonpasteelectrodeavoltammetricstudy |