Thrombophilia in the pathogenesis of fetal growth retardation
Fetal growth retardation (FGR) is a complication of pregnancy that determines perinatal morbidity and mortality. It is a complex and multifaceted medical problem that does not lose its relevance. Impaired fetal development and delayed growth result from various etiopathogenesis of pathological proce...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2021-05-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/973 |
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| author | E. A. Orudzhova N. A. Samburova E. V. Anichkova K. E. Gotsiridze V. O. Bitsadze |
| author_facet | E. A. Orudzhova N. A. Samburova E. V. Anichkova K. E. Gotsiridze V. O. Bitsadze |
| author_sort | E. A. Orudzhova |
| collection | DOAJ |
| description | Fetal growth retardation (FGR) is a complication of pregnancy that determines perinatal morbidity and mortality. It is a complex and multifaceted medical problem that does not lose its relevance. Impaired fetal development and delayed growth result from various etiopathogenesis of pathological processes occurring in the "mother–placenta–fetus" interface. Thrombophilia is one of the factors that can initiate disturbed placental function and the utero-placental blood flow. Here we describe the clinical FGR variants and etiopathogenetic factors of developing this complication of pregnancy (placental, maternal, and fetal). Special attention is paid to genetic and acquired thrombophilia (due to the circulation of antiphospholipid antibodies) and their role in development of such complication of pregnancy. |
| format | Article |
| id | doaj-art-e1b792a738e64901a15d17303e510c15 |
| institution | Kabale University |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2021-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-e1b792a738e64901a15d17303e510c152025-08-20T03:39:36ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942021-05-0115218920010.17749/2313-7347/ob.gyn.rep.2021.223643Thrombophilia in the pathogenesis of fetal growth retardationE. A. Orudzhova0N. A. Samburova1E. V. Anichkova2K. E. Gotsiridze3V. O. Bitsadze4Maternity Hospital № 1 – Branch of Vorokhobov City Clinical Hospital № 67, Moscow Healthcare DepartmentSechenov UniversitySechenov UniversityChachava ClinicSechenov UniversityFetal growth retardation (FGR) is a complication of pregnancy that determines perinatal morbidity and mortality. It is a complex and multifaceted medical problem that does not lose its relevance. Impaired fetal development and delayed growth result from various etiopathogenesis of pathological processes occurring in the "mother–placenta–fetus" interface. Thrombophilia is one of the factors that can initiate disturbed placental function and the utero-placental blood flow. Here we describe the clinical FGR variants and etiopathogenetic factors of developing this complication of pregnancy (placental, maternal, and fetal). Special attention is paid to genetic and acquired thrombophilia (due to the circulation of antiphospholipid antibodies) and their role in development of such complication of pregnancy.https://www.gynecology.su/jour/article/view/973fetal growth retardationfgrgenetic thrombophiliaantiphospholipid syndromeantiphospholipid antibodies |
| spellingShingle | E. A. Orudzhova N. A. Samburova E. V. Anichkova K. E. Gotsiridze V. O. Bitsadze Thrombophilia in the pathogenesis of fetal growth retardation Акушерство, гинекология и репродукция fetal growth retardation fgr genetic thrombophilia antiphospholipid syndrome antiphospholipid antibodies |
| title | Thrombophilia in the pathogenesis of fetal growth retardation |
| title_full | Thrombophilia in the pathogenesis of fetal growth retardation |
| title_fullStr | Thrombophilia in the pathogenesis of fetal growth retardation |
| title_full_unstemmed | Thrombophilia in the pathogenesis of fetal growth retardation |
| title_short | Thrombophilia in the pathogenesis of fetal growth retardation |
| title_sort | thrombophilia in the pathogenesis of fetal growth retardation |
| topic | fetal growth retardation fgr genetic thrombophilia antiphospholipid syndrome antiphospholipid antibodies |
| url | https://www.gynecology.su/jour/article/view/973 |
| work_keys_str_mv | AT eaorudzhova thrombophiliainthepathogenesisoffetalgrowthretardation AT nasamburova thrombophiliainthepathogenesisoffetalgrowthretardation AT evanichkova thrombophiliainthepathogenesisoffetalgrowthretardation AT kegotsiridze thrombophiliainthepathogenesisoffetalgrowthretardation AT vobitsadze thrombophiliainthepathogenesisoffetalgrowthretardation |