HOXA5 Derives the Malignant Progression and Cisplatin Resistance of Esophageal Squamous Cell Carcinoma by Regulating USP18‐Mediated IFI27 Deubiquitination

HOXA5 Derives the Malignant Progression and Cisplatin Resistance of Esophageal Squamous Cell Carcinoma by Regulating USP18‐Mediated IFI27 Deubiquitination

ABSTRACT Background Chemo‐resistance is a major obstacle to the treatment of esophageal squamous cell carcinoma (ESCC). Interferon alpha‐inducible protein 27 (IFI27) has been reported to be associated with ESCC progression. This study is designed to explore the role and mechanism of IFI27 in the cis...

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Bibliographic Details
Main Authors: Qiang Wang, Shiheng Ren, Zheng Pan, Yuxin Chen, Xiangyan Liu
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Thoracic Cancer
Subjects:
DDP resistance mechanism
deubiquitination
ESCC
HOXA5
IFI27
proliferation
Online Access:https://doi.org/10.1111/1759-7714.70013
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