Concomitant Interstitial Lung Disease with Psoriasis

Background. We encounter interstitial lung disease (ILD) patients with psoriasis. The aim of this case series was to examine clinical and radiographic characteristics of patients with concomitant psoriasis and ILD. Methods. This is a retrospective review of our institutional experience of ILD concom...

Full description

Saved in:
Bibliographic Details
Main Authors: Genta Ishikawa, Sakshi Dua, Aditi Mathur, Samuel O. Acquah, Mary Salvatore, Mary B. Beasley, Maria L. Padilla
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2019/5919304
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849691545619398656
author Genta Ishikawa
Sakshi Dua
Aditi Mathur
Samuel O. Acquah
Mary Salvatore
Mary B. Beasley
Maria L. Padilla
author_facet Genta Ishikawa
Sakshi Dua
Aditi Mathur
Samuel O. Acquah
Mary Salvatore
Mary B. Beasley
Maria L. Padilla
author_sort Genta Ishikawa
collection DOAJ
description Background. We encounter interstitial lung disease (ILD) patients with psoriasis. The aim of this case series was to examine clinical and radiographic characteristics of patients with concomitant psoriasis and ILD. Methods. This is a retrospective review of our institutional experience of ILD concomitant with psoriasis, from the database in the Advanced Lung/Interstitial Lung Disease Program at the Mount Sinai Hospital. Out of 447 ILD patients, we identified 21 (4.7%) with antecedent or concomitant diagnosis of psoriasis. Clinical, radiographic, pathological, and outcome data were abstracted from our medical records. Results. Median age was 66 years (range, 46–86) and 14 (66.7%) were male. Thirteen (61.9%) had not previously or concomitantly been exposed to immunosuppressive therapy directed against psoriasis. Two (9.5%) ultimately died. Clinical diagnosis of ILD included idiopathic pulmonary fibrosis, 11 (52.4%); nonspecific interstitial pneumonia (NSIP), 2 (9.5%); cryptogenic organizing pneumonia, 2 (9.5%); chronic hypersensitivity pneumonitis, 2 (9.5%); and the others, while radiographic diagnosis included usual interstitial pneumonia pattern, 9 (42.9%); NSIP pattern, 6 (28.6%); organizing pneumonia pattern, 4 (19.0%); hypersensitivity pneumonitis pattern, 2 (9.5%); and the others. Conclusions. We report 21 ILD cases with antecedent or concomitant diagnosis of psoriasis. Further prospective studies are required to determine the association between ILD and psoriasis.
format Article
id doaj-art-e1a70b0e6b114b7aa352f69ace0c93dc
institution DOAJ
issn 1198-2241
1916-7245
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Canadian Respiratory Journal
spelling doaj-art-e1a70b0e6b114b7aa352f69ace0c93dc2025-08-20T03:20:59ZengWileyCanadian Respiratory Journal1198-22411916-72452019-01-01201910.1155/2019/59193045919304Concomitant Interstitial Lung Disease with PsoriasisGenta Ishikawa0Sakshi Dua1Aditi Mathur2Samuel O. Acquah3Mary Salvatore4Mary B. Beasley5Maria L. Padilla6Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USADivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USADivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USADivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Radiology, Columbia University Medical Center, New York, NY, USADepartment of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USADivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USABackground. We encounter interstitial lung disease (ILD) patients with psoriasis. The aim of this case series was to examine clinical and radiographic characteristics of patients with concomitant psoriasis and ILD. Methods. This is a retrospective review of our institutional experience of ILD concomitant with psoriasis, from the database in the Advanced Lung/Interstitial Lung Disease Program at the Mount Sinai Hospital. Out of 447 ILD patients, we identified 21 (4.7%) with antecedent or concomitant diagnosis of psoriasis. Clinical, radiographic, pathological, and outcome data were abstracted from our medical records. Results. Median age was 66 years (range, 46–86) and 14 (66.7%) were male. Thirteen (61.9%) had not previously or concomitantly been exposed to immunosuppressive therapy directed against psoriasis. Two (9.5%) ultimately died. Clinical diagnosis of ILD included idiopathic pulmonary fibrosis, 11 (52.4%); nonspecific interstitial pneumonia (NSIP), 2 (9.5%); cryptogenic organizing pneumonia, 2 (9.5%); chronic hypersensitivity pneumonitis, 2 (9.5%); and the others, while radiographic diagnosis included usual interstitial pneumonia pattern, 9 (42.9%); NSIP pattern, 6 (28.6%); organizing pneumonia pattern, 4 (19.0%); hypersensitivity pneumonitis pattern, 2 (9.5%); and the others. Conclusions. We report 21 ILD cases with antecedent or concomitant diagnosis of psoriasis. Further prospective studies are required to determine the association between ILD and psoriasis.http://dx.doi.org/10.1155/2019/5919304
spellingShingle Genta Ishikawa
Sakshi Dua
Aditi Mathur
Samuel O. Acquah
Mary Salvatore
Mary B. Beasley
Maria L. Padilla
Concomitant Interstitial Lung Disease with Psoriasis
Canadian Respiratory Journal
title Concomitant Interstitial Lung Disease with Psoriasis
title_full Concomitant Interstitial Lung Disease with Psoriasis
title_fullStr Concomitant Interstitial Lung Disease with Psoriasis
title_full_unstemmed Concomitant Interstitial Lung Disease with Psoriasis
title_short Concomitant Interstitial Lung Disease with Psoriasis
title_sort concomitant interstitial lung disease with psoriasis
url http://dx.doi.org/10.1155/2019/5919304
work_keys_str_mv AT gentaishikawa concomitantinterstitiallungdiseasewithpsoriasis
AT sakshidua concomitantinterstitiallungdiseasewithpsoriasis
AT aditimathur concomitantinterstitiallungdiseasewithpsoriasis
AT samueloacquah concomitantinterstitiallungdiseasewithpsoriasis
AT marysalvatore concomitantinterstitiallungdiseasewithpsoriasis
AT marybbeasley concomitantinterstitiallungdiseasewithpsoriasis
AT marialpadilla concomitantinterstitiallungdiseasewithpsoriasis