The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis

The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulati...

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Main Authors: O. V. Voronkova, O. I. Urazova, R. R. Khasanova, V. V. Novitsky, Ye. G. Churina, I. O. Naslednikova, O. V. Filinyuk, V. A. Serebryakova, Yu. V. Kolobovnikova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-02-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/1308
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author O. V. Voronkova
O. I. Urazova
R. R. Khasanova
V. V. Novitsky
Ye. G. Churina
I. O. Naslednikova
O. V. Filinyuk
V. A. Serebryakova
Yu. V. Kolobovnikova
author_facet O. V. Voronkova
O. I. Urazova
R. R. Khasanova
V. V. Novitsky
Ye. G. Churina
I. O. Naslednikova
O. V. Filinyuk
V. A. Serebryakova
Yu. V. Kolobovnikova
author_sort O. V. Voronkova
collection DOAJ
description The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.
format Article
id doaj-art-e19c41fb4fcd46e99dc319215ec501d9
institution DOAJ
issn 1682-0363
1819-3684
language English
publishDate 2011-02-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-e19c41fb4fcd46e99dc319215ec501d92025-08-20T03:02:23ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-02-01101121710.20538/1682-0363-2011-1-12-17831The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosisO. V. Voronkova0O. I. Urazova1R. R. Khasanova2V. V. Novitsky3Ye. G. Churina4I. O. Naslednikova5O. V. Filinyuk6V. A. Serebryakova7Yu. V. Kolobovnikova8Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетThe results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.https://bulletin.ssmu.ru/jour/article/view/1308mycobacterium tuberculosisgenetic typinggenetic profiledrag resistance
spellingShingle O. V. Voronkova
O. I. Urazova
R. R. Khasanova
V. V. Novitsky
Ye. G. Churina
I. O. Naslednikova
O. V. Filinyuk
V. A. Serebryakova
Yu. V. Kolobovnikova
The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
Бюллетень сибирской медицины
mycobacterium tuberculosis
genetic typing
genetic profile
drag resistance
title The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_full The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_fullStr The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_full_unstemmed The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_short The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis
title_sort genotypical characteristic of m tuberculosis aetiological agents of acute progressive destructive pulmonary tuberculosis
topic mycobacterium tuberculosis
genetic typing
genetic profile
drag resistance
url https://bulletin.ssmu.ru/jour/article/view/1308
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