Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia
<b>Background/Objectives</b>: To evaluate the visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) surgery and refractive lens exchange (RLE) surgery in moderate to high myopia patients. <b>Methods</b>: A retrospective cohort study was performed, and...
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MDPI AG
2024-12-01
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| author | Chia-Yi Lee Shun-Fa Yang Hung-Chi Chen Ie-Bin Lian Jing-Yang Huang Chao-Kai Chang |
| author_facet | Chia-Yi Lee Shun-Fa Yang Hung-Chi Chen Ie-Bin Lian Jing-Yang Huang Chao-Kai Chang |
| author_sort | Chia-Yi Lee |
| collection | DOAJ |
| description | <b>Background/Objectives</b>: To evaluate the visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) surgery and refractive lens exchange (RLE) surgery in moderate to high myopia patients. <b>Methods</b>: A retrospective cohort study was performed, and patients receiving KLEx or RLE surgeries with myopia within −3.00 to −10.00 diopter (D) were enrolled. A total of 19 and 35 patients were put into the RLE and KLEx groups after exclusion. The main outcomes are postoperative uncorrected visual acuity (UDVA), the spherical equivalent (SE), and residual astigmatism via vector analysis. Fisher’s exact test and the Mann–Whitney U test were utilized for the statistical analysis. <b>Results</b>: The percentages of patients who reached UDVA results of more than 20/25 and 20/20 were statistically similar between groups (both <i>p</i> > 0.05), and the percentages of patients who reached SE results within ±0.50 D and ±1.00 D were statistically similar between groups (both <i>p</i> > 0.05). The change in SE in the KLEx group was lesser compared to that in the RLE group (<i>p</i> = 0.021). The vector analysis showed a lower DV and ME and a higher CoI in the KLEx group than in the RLE group (all <i>p</i> < 0.05). The percentage of patients who reached specific UDVA and SE thresholds were statistically similar between groups with different myopia degrees (all <i>p</i> > 0.05). <b>Conclusions</b>: The postoperative visual and refractive outcomes between RLE and KLEx surgeries are grossly comparable, while the KLEx may have a slight advantage in astigmatism correction. |
| format | Article |
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| institution | Kabale University |
| issn | 2075-4418 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-e189de59a82546b38c3a9d808f6a7ec72025-01-10T13:16:33ZengMDPI AGDiagnostics2075-44182024-12-011514310.3390/diagnostics15010043Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High MyopiaChia-Yi Lee0Shun-Fa Yang1Hung-Chi Chen2Ie-Bin Lian3Jing-Yang Huang4Chao-Kai Chang5Institute of Medicine, Chung Shan Medical University, Taichung 40201, TaiwanInstitute of Medicine, Chung Shan Medical University, Taichung 40201, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, TaiwanInstitute of Statistical and Information Science, National Changhua University of Education, Chunghua 50007, TaiwanDepartment of Medical Research, Chung Shan Medical University Hospital, Taichung 40201, TaiwanNobel Eye Institute, Taipei 10041, Taiwan<b>Background/Objectives</b>: To evaluate the visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) surgery and refractive lens exchange (RLE) surgery in moderate to high myopia patients. <b>Methods</b>: A retrospective cohort study was performed, and patients receiving KLEx or RLE surgeries with myopia within −3.00 to −10.00 diopter (D) were enrolled. A total of 19 and 35 patients were put into the RLE and KLEx groups after exclusion. The main outcomes are postoperative uncorrected visual acuity (UDVA), the spherical equivalent (SE), and residual astigmatism via vector analysis. Fisher’s exact test and the Mann–Whitney U test were utilized for the statistical analysis. <b>Results</b>: The percentages of patients who reached UDVA results of more than 20/25 and 20/20 were statistically similar between groups (both <i>p</i> > 0.05), and the percentages of patients who reached SE results within ±0.50 D and ±1.00 D were statistically similar between groups (both <i>p</i> > 0.05). The change in SE in the KLEx group was lesser compared to that in the RLE group (<i>p</i> = 0.021). The vector analysis showed a lower DV and ME and a higher CoI in the KLEx group than in the RLE group (all <i>p</i> < 0.05). The percentage of patients who reached specific UDVA and SE thresholds were statistically similar between groups with different myopia degrees (all <i>p</i> > 0.05). <b>Conclusions</b>: The postoperative visual and refractive outcomes between RLE and KLEx surgeries are grossly comparable, while the KLEx may have a slight advantage in astigmatism correction.https://www.mdpi.com/2075-4418/15/1/43keratorefractive lenticule extractionrefractive lens exchangeastigmatismuncorrected distance visual acuityspherical equivalent |
| spellingShingle | Chia-Yi Lee Shun-Fa Yang Hung-Chi Chen Ie-Bin Lian Jing-Yang Huang Chao-Kai Chang Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia Diagnostics keratorefractive lenticule extraction refractive lens exchange astigmatism uncorrected distance visual acuity spherical equivalent |
| title | Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia |
| title_full | Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia |
| title_fullStr | Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia |
| title_full_unstemmed | Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia |
| title_short | Comparison of Visual and Refractive Outcomes Between Refractive Lens Exchange and Keratorefractive Lenticule Extraction Surgery in Moderate to High Myopia |
| title_sort | comparison of visual and refractive outcomes between refractive lens exchange and keratorefractive lenticule extraction surgery in moderate to high myopia |
| topic | keratorefractive lenticule extraction refractive lens exchange astigmatism uncorrected distance visual acuity spherical equivalent |
| url | https://www.mdpi.com/2075-4418/15/1/43 |
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