MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN
Examination of 73 children of 8–12 years of age was conducted in order to study morphological characteristics of erythrocytes at undifferentiated connective tissue dysplasia (UCTD). Scanning electron microscopy revealed significant alterations of surface architectonics of red blood cells, characteri...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2014-01-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/142 |
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| author | D. A. Ponomareva T. A. Nagayeva I. I. Balasheva N. M. Shevtsova |
| author_facet | D. A. Ponomareva T. A. Nagayeva I. I. Balasheva N. M. Shevtsova |
| author_sort | D. A. Ponomareva |
| collection | DOAJ |
| description | Examination of 73 children of 8–12 years of age was conducted in order to study morphological characteristics of erythrocytes at undifferentiated connective tissue dysplasia (UCTD). Scanning electron microscopy revealed significant alterations of surface architectonics of red blood cells, characterized by reduction in the number of discocytes and increase in the number of transformed and degenerative cell forms in the group of children with UCTD without development of anemic syndrome. The most intensive morphological presentation disorders of red blood cells were registered in children with UCTD and anemic syndrome. The article shows that structural inferiority of erythrocyte membranes is a pathogenetic anemia development factor in children with connective tissue dysplasia |
| format | Article |
| id | doaj-art-e185ea33051e4541b6d8fd5dad775647 |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2014-01-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-e185ea33051e4541b6d8fd5dad7756472025-08-20T03:36:53ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892014-01-01111636510.15690/pf.v11i1.898142MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREND. A. Ponomareva0T. A. Nagayeva1I. I. Balasheva2N. M. Shevtsova3Siberian State Medical University, TomskSiberian State Medical University, Tomsk, Russian FederationSiberian State Medical University, Tomsk, Russian FederationSiberian State Medical University, Tomsk, Russian FederationExamination of 73 children of 8–12 years of age was conducted in order to study morphological characteristics of erythrocytes at undifferentiated connective tissue dysplasia (UCTD). Scanning electron microscopy revealed significant alterations of surface architectonics of red blood cells, characterized by reduction in the number of discocytes and increase in the number of transformed and degenerative cell forms in the group of children with UCTD without development of anemic syndrome. The most intensive morphological presentation disorders of red blood cells were registered in children with UCTD and anemic syndrome. The article shows that structural inferiority of erythrocyte membranes is a pathogenetic anemia development factor in children with connective tissue dysplasiahttps://www.pedpharma.ru/jour/article/view/142childrenconnective tissue dysplasiaerythrocyteselectron microscopy |
| spellingShingle | D. A. Ponomareva T. A. Nagayeva I. I. Balasheva N. M. Shevtsova MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN Педиатрическая фармакология children connective tissue dysplasia erythrocytes electron microscopy |
| title | MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN |
| title_full | MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN |
| title_fullStr | MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN |
| title_full_unstemmed | MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN |
| title_short | MORPHOLOGICAL CHARACTERISTICS OF ERYTHROCYTES AT UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA IN CHILDREN |
| title_sort | morphological characteristics of erythrocytes at undifferentiated connective tissue dysplasia in children |
| topic | children connective tissue dysplasia erythrocytes electron microscopy |
| url | https://www.pedpharma.ru/jour/article/view/142 |
| work_keys_str_mv | AT daponomareva morphologicalcharacteristicsoferythrocytesatundifferentiatedconnectivetissuedysplasiainchildren AT tanagayeva morphologicalcharacteristicsoferythrocytesatundifferentiatedconnectivetissuedysplasiainchildren AT iibalasheva morphologicalcharacteristicsoferythrocytesatundifferentiatedconnectivetissuedysplasiainchildren AT nmshevtsova morphologicalcharacteristicsoferythrocytesatundifferentiatedconnectivetissuedysplasiainchildren |