Development and application of a whole transcriptome sequencing assay for the detection of gene fusions in clinical cancer specimens

Development and application of a whole transcriptome sequencing assay for the detection of gene fusions in clinical cancer specimens

Abstract Background Gene fusions are an important driver of cancer and require rapid and accurate detection to guide clinical decisions. However, the performance characteristics of whole transcriptome sequencing (WTS) for the detection of gene fusions have not been thoroughly investigated. Methods W...

Full description

Saved in:
Bibliographic Details
Main Authors: Songchen Zhao, Xinhua Du, Yan Zhang, Jing Bai, Lu Meng, Xuefei Li, Jiaxin Ma, HeYu Sheng, Xiaorui Fu, Yanfang Guan, Yuting Yi, Ling Yang, Xuefeng Xia, Xin Yi, Xinxin Tan, Caicun Zhou
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Gene fusions
WTS assay
Actionable fusions
Cancer specimens
Online Access:https://doi.org/10.1186/s12885-025-14186-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items