PRALINE: study protocol for a phase IIb inpatient stroke rehabilitation randomized controlled trial investigating longitudinal outcomes after progressive abduction loading therapy

PRALINE: study protocol for a phase IIb inpatient stroke rehabilitation randomized controlled trial investigating longitudinal outcomes after progressive abduction loading therapy

Abstract Background Stroke is the leading cause of long-term disability with paucity of evidence-based interventions for individuals with severe upper extremity impairment in the affected arm. Loss of independent joint control limits reaching distance and velocity contributing to activity and partic...

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Main Authors: Heidi R. Roth, Carolina Carmona, Gina Clark, Jane E. Gyarmaty, Julius P. A. Dewald, Elise Giblin, Richard L. Harvey, Jacquelyn Jaskiewicz, Kwang-Youn A. Kim, Nicola Lancki, Alexis Luhrsen, Ahalya Mandana, Deepali Manikonda, Andrew Morris, Sonia Sheth, Mary Ellen Stoykov, Amanda C. Young, Donna Zielke, Michael D. Ellis
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Trials
Subjects:
Stroke
Upper extremity
Synergy
Rehabilitation
Online Access:https://doi.org/10.1186/s13063-025-08969-6
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