Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trial
Background: Pain plays a significant role in emergency department (ED) visits, however safe and effective nonpharmacologic options are needed. Prior studies of acupuncture in the ED reported pain reduction with minimal side effects, but most were small and single site. Methods: We conducted ACUITY,...
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Elsevier
2024-12-01
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| Series: | Integrative Medicine Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213422024000751 |
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| author | Jeffery A. Dusek Gene A. Kallenberg Alan B. Storrow Robert M. Hughes Christopher J. Coyne David R. Vago Arya Nielsen Alison Karasz Ryung S. Kim Jessica Surdam Tracy Segall Kiran A. Faryar Natalie L. Dyer Bruce A. Barton M. Diane McKee |
| author_facet | Jeffery A. Dusek Gene A. Kallenberg Alan B. Storrow Robert M. Hughes Christopher J. Coyne David R. Vago Arya Nielsen Alison Karasz Ryung S. Kim Jessica Surdam Tracy Segall Kiran A. Faryar Natalie L. Dyer Bruce A. Barton M. Diane McKee |
| author_sort | Jeffery A. Dusek |
| collection | DOAJ |
| description | Background: Pain plays a significant role in emergency department (ED) visits, however safe and effective nonpharmacologic options are needed. Prior studies of acupuncture in the ED reported pain reduction with minimal side effects, but most were small and single site. Methods: We conducted ACUITY, a prospectively designed multi-center feasibility RCT. Our goal was to recruit 165 adults with acute non-emergent pain ≥4 on a 0–10-point scale at three EDs affiliated with BraveNet Practice Based Research Network. At baseline and 45–60 min later (post), participants self-assessed their pain and anxiety using a 0–10 rating scale. The primary feasibility outcome was recruitment of participants, whereas secondary outcomes were retention, and participant/provider acceptability. Results: From May 3, 2021, to September 24, 2022, 632 eligible individuals were approached and 165 enrolled (165/632: 26.1 %), meeting our recruitment goal. Notably, 42.4 % of enrollees were Black/African American, 42.4 % were White/Caucasian, and 13.9 % were Hispanic/Latino. Participants were randomized to Acupuncture (n = 83) or Usual care (n = 82), of which 151 (91.5 %) and 128 (77.6 %) provided pain and anxiety scores at post-treatment and 1-week respectively. Acupuncture was rated acceptable to participants and providers. Mean pain ratings (pre-to-post) were 7.4 (2.2) to 4.8 (2.8) for acupuncture and 7.1 (2.3) to 6.4 (2.5) for usual care. Mean anxiety ratings (pre-to-post) were 4.5 (3.4) to 2.5 (2.6) for acupuncture and 4.1 (3.4) to 3.5 (3.2) for usual care. Conclusion: Successful completion of ACUITY indicates we have the expertise and preliminary data to conduct a future definitive, multi-center RCT. Trial registration: Clinical trials.gov: NCT04880733. |
| format | Article |
| id | doaj-art-e17edff9e6994583a59f798fec25a90f |
| institution | DOAJ |
| issn | 2213-4220 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
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| series | Integrative Medicine Research |
| spelling | doaj-art-e17edff9e6994583a59f798fec25a90f2025-08-20T03:21:06ZengElsevierIntegrative Medicine Research2213-42202024-12-0113410109510.1016/j.imr.2024.101095Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trialJeffery A. Dusek0Gene A. Kallenberg1Alan B. Storrow2Robert M. Hughes3Christopher J. Coyne4David R. Vago5Arya Nielsen6Alison Karasz7Ryung S. Kim8Jessica Surdam9Tracy Segall10Kiran A. Faryar11Natalie L. Dyer12Bruce A. Barton13M. Diane McKee14Department of Medicine, University of California- Irvine, Irvine, CA, USA; Suan Samueli Integrative Health Institute, University of California- Irvine, Irvine, CA, USA; Corresponding author at: Susan Samueli Integrative Health Institute, University of California Irvine, 856 Health Sciences Road, Irvine, CA 92617, USA.Department of Family Medicine, University of California San Diego, La Jolla, CA, USADepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Emergency Medicine, Cleveland Medical Center, University Hospitals, Cleveland, OH, USA; Department of Emergency Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USADepartment of Emergency Medicine and Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USADepartment of Psychology, Vanderbilt University, Nashville, TN, USADepartment of Family Medicine & Community Health, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Family Medicine and Community Health, Chan School of Medicine, University of Massachusetts, Worcester, MA, USA; Department of Family Medicine and Social Medicine, Albert Einstein College of Medicine/Montefiore, New York, NY, USADepartment of Epidemiology and Population Health and Institute of Clinical and Translational Research, Albert Einstein College of Medicine/Montefiore, New York, NY, USAUH Connor Whole Health, University Hospitals, Cleveland, OH, USAUH Connor Whole Health, University Hospitals, Cleveland, OH, USADepartment of Emergency Medicine, Cleveland Medical Center, University Hospitals, Cleveland, OH, USA; Department of Emergency Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USASuan Samueli Integrative Health Institute, University of California- Irvine, Irvine, CA, USADepartment of Population and Quantitative Health Sciences, Chan School of Medicine, University of Massachusetts, Worcester, MA, USADepartment of Family Medicine and Community Health, Chan School of Medicine, University of Massachusetts, Worcester, MA, USABackground: Pain plays a significant role in emergency department (ED) visits, however safe and effective nonpharmacologic options are needed. Prior studies of acupuncture in the ED reported pain reduction with minimal side effects, but most were small and single site. Methods: We conducted ACUITY, a prospectively designed multi-center feasibility RCT. Our goal was to recruit 165 adults with acute non-emergent pain ≥4 on a 0–10-point scale at three EDs affiliated with BraveNet Practice Based Research Network. At baseline and 45–60 min later (post), participants self-assessed their pain and anxiety using a 0–10 rating scale. The primary feasibility outcome was recruitment of participants, whereas secondary outcomes were retention, and participant/provider acceptability. Results: From May 3, 2021, to September 24, 2022, 632 eligible individuals were approached and 165 enrolled (165/632: 26.1 %), meeting our recruitment goal. Notably, 42.4 % of enrollees were Black/African American, 42.4 % were White/Caucasian, and 13.9 % were Hispanic/Latino. Participants were randomized to Acupuncture (n = 83) or Usual care (n = 82), of which 151 (91.5 %) and 128 (77.6 %) provided pain and anxiety scores at post-treatment and 1-week respectively. Acupuncture was rated acceptable to participants and providers. Mean pain ratings (pre-to-post) were 7.4 (2.2) to 4.8 (2.8) for acupuncture and 7.1 (2.3) to 6.4 (2.5) for usual care. Mean anxiety ratings (pre-to-post) were 4.5 (3.4) to 2.5 (2.6) for acupuncture and 4.1 (3.4) to 3.5 (3.2) for usual care. Conclusion: Successful completion of ACUITY indicates we have the expertise and preliminary data to conduct a future definitive, multi-center RCT. Trial registration: Clinical trials.gov: NCT04880733.http://www.sciencedirect.com/science/article/pii/S2213422024000751Acute painNonpharmacologicRandomized controlled trialIntegrative medicine |
| spellingShingle | Jeffery A. Dusek Gene A. Kallenberg Alan B. Storrow Robert M. Hughes Christopher J. Coyne David R. Vago Arya Nielsen Alison Karasz Ryung S. Kim Jessica Surdam Tracy Segall Kiran A. Faryar Natalie L. Dyer Bruce A. Barton M. Diane McKee Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trial Integrative Medicine Research Acute pain Nonpharmacologic Randomized controlled trial Integrative medicine |
| title | Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trial |
| title_full | Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trial |
| title_fullStr | Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trial |
| title_full_unstemmed | Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trial |
| title_short | Acupuncture in the emergency department (ACUITY): Results from a BraveNet multi-center feasibility randomized controlled trial |
| title_sort | acupuncture in the emergency department acuity results from a bravenet multi center feasibility randomized controlled trial |
| topic | Acute pain Nonpharmacologic Randomized controlled trial Integrative medicine |
| url | http://www.sciencedirect.com/science/article/pii/S2213422024000751 |
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