Efficacy and Immunological Impact of Intrathecal Baclofen Pumps in Managing Spasticity in Multiple Sclerosis in Adult Patients: A Systematic Review

Efficacy and Immunological Impact of Intrathecal Baclofen Pumps in Managing Spasticity in Multiple Sclerosis in Adult Patients: A Systematic Review

Background/Objectives: Multiple sclerosis (MS) is a chronic autoimmune disease marked by inflammatory demyelination in the central nervous system, leading to debilitating spasticity. Managing spasticity in MS remains a challenge, and intrathecal baclofen (ITB) therapy has emerged as a potential targ...

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Main Authors: Billy McBenedict, Wilhelmina Hauwanga, Anna Pogodina, Jeshua Nathaniel Devan, Kang Suen Goh, Ryan Chun Chien Yau, Berley Alphonse, Lorena Adolphsson, Bruno Lima Pessôa
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Sclerosis
Subjects:
multiple sclerosis
spasticity
intrathecal baclofen
immune modulation
neuroinflammation
central nervous system
Online Access:https://www.mdpi.com/2813-3064/3/1/2
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