Intraventricular continuous BDNF administration ameliorates neuroinflammation and enhances neurogenesis against rodent intracerebral hemorrhage model

Intraventricular continuous BDNF administration ameliorates neuroinflammation and enhances neurogenesis against rodent intracerebral hemorrhage model

ObjectiveBrain-derived neurotrophic factor (BDNF) is a pivotal growth factor for neuronal survival; however, its precise role following intracerebral hemorrhage (ICH) remains poorly understood. This study sought to investigate whether intraventricular administration of BDNF could enhance neurogenesi...

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Bibliographic Details
Main Authors: Ting-Chun Lin, Masahito Kawabori, Erika Yoshie, Yo Nakahara, Li-Kai Tsai, Miki Fujimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neurology
Subjects:
intracerebral hemorrhage
brain derived neurotrophic factor
intraventricular transplantation
inflammation
neurogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1606606/full
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