Respiratory syncytial virus (RSV) enhances translation of virus-resembling AU-rich host transcripts

Respiratory syncytial virus (RSV) enhances translation of virus-resembling AU-rich host transcripts

Abstract Background Viruses strongly rely on the host’s translational machinery to produce viral proteins required for replication. However, it is unknown how viruses that do not globally inhibit cap-dependent translation compete with abundant host transcripts for ribosomes. Viral infection often tr...

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Bibliographic Details
Main Authors: Kyra Kerkhofs, Nicholas R. Guydosh, Mark A. Bayfield
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Virology Journal
Subjects:
RSV
VSV
Translation efficiency
Polysome profiling
High-throughput sequencing
AU-rich transcripts
Online Access:https://doi.org/10.1186/s12985-025-02838-z
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