Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic
Abstract Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances in coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise in the incidence o...
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Nature Portfolio
2025-01-01
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| Online Access: | https://doi.org/10.1038/s41598-024-84983-z |
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| author | Giuseppe Nasso Ignazio Condello Walter Vignaroli Andrea Antonazzo Francesco Bartolomucci Barbara Pala Claudio Larosa Annachiara Pingitore Vincenzo Amodeo Vincenzo Montemurro Mizar D’Abramo Roberto Ceravolo Domenica Donato Pasquale Fratto Maria Grazia De Rosis Giuseppe Diaferia Rita Torraco Gaetano Contegiacomo Guido Lembo Mario Siro Brigiani Giuseppe Santarpino Giuseppe Speziale |
| author_facet | Giuseppe Nasso Ignazio Condello Walter Vignaroli Andrea Antonazzo Francesco Bartolomucci Barbara Pala Claudio Larosa Annachiara Pingitore Vincenzo Amodeo Vincenzo Montemurro Mizar D’Abramo Roberto Ceravolo Domenica Donato Pasquale Fratto Maria Grazia De Rosis Giuseppe Diaferia Rita Torraco Gaetano Contegiacomo Guido Lembo Mario Siro Brigiani Giuseppe Santarpino Giuseppe Speziale |
| author_sort | Giuseppe Nasso |
| collection | DOAJ |
| description | Abstract Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances in coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise in the incidence of post-MI VSD, likely driven by delays in seeking treatment. This study retrospectively analyzed 10 cases of post-MI VSD treated at our hospitals from March 2018 to August 2023, comparing incidence rates across pre-pandemic, pandemic, and post-pandemic periods. The findings revealed a notable increase in VSD cases during the pandemic, with six cases occurring in two years, compared to only two cases in each of the pre-pandemic and post-pandemic periods. Despite these fluctuations, surgical intervention remained a crucial and effective treatment, with 60% of patients surviving the 30-day follow-up. The study underscores the impact of delayed treatment on VSD incidence during the pandemic and highlights the critical need for timely medical intervention to manage severe MI complications effectively. |
| format | Article |
| id | doaj-art-e176e0c9b258420a8773d73f4f714236 |
| institution | OA Journals |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-e176e0c9b258420a8773d73f4f7142362025-08-20T01:47:59ZengNature PortfolioScientific Reports2045-23222025-01-011511810.1038/s41598-024-84983-zPost-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemicGiuseppe Nasso0Ignazio Condello1Walter Vignaroli2Andrea Antonazzo3Francesco Bartolomucci4Barbara Pala5Claudio Larosa6Annachiara Pingitore7Vincenzo Amodeo8Vincenzo Montemurro9Mizar D’Abramo10Roberto Ceravolo11Domenica Donato12Pasquale Fratto13Maria Grazia De Rosis14Giuseppe Diaferia15Rita Torraco16Gaetano Contegiacomo17Guido Lembo18Mario Siro Brigiani19Giuseppe Santarpino20Giuseppe Speziale21Department of Cardiovascular Surgery, GVM Care & Research, Anthea HospitalDepartment of Cardiovascular Surgery, GVM Care & Research, Anthea HospitalDepartment of Cardiovascular Surgery, GVM Care & Research, San Carlo di NancyCardioThoracoVascular Department, Great Metropolitan Hospital “Bianchi Melacrino Morelli”Department of Cardiology, Hospital of AndriaDivision of Cardiology, Department of Clinical and Molecular Medicine, Sapienza University of Rome, Sant’Andrea HospitalDepartment of Cardiology, Hospital of AndriaDepartment of General and Specialistic Surgery “Paride Stefanini”, Sapienza University of RomeDepartment of Cardiology, “Santa Maria degli Ungheresi” HospitalDepartment of cardiology, CDC Scilla ASP Reggio CalabriaDepartment of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of RomeDepartment of Cardiology, Hospital Giovanni Paolo IICardioThoracoVascular Department, Great Metropolitan Hospital “Bianchi Melacrino Morelli”CardioThoracoVascular Department, Great Metropolitan Hospital “Bianchi Melacrino Morelli”Azienda Sanitaria LocaleDepartment of Cardiology, “M. Di Miccoli” HospitalDepartment of Cardiology, “M. Di Miccoli” HospitalDepartment of Cardiovascular Surgery, GVM Care & Research, Anthea HospitalDepartment of Cardiovascular Surgery, GVM Care & Research, Anthea HospitalDepartment of Cardiovascular Surgery, GVM Care & Research, Anthea HospitalDepartment of Cardiovascular Surgery, GVM Care & Research, Anthea HospitalDepartment of Cardiovascular Surgery, GVM Care & Research, Anthea HospitalAbstract Ventricular septal defect (VSD) is a serious complication of myocardial infarction (MI), with its global incidence significantly reduced in recent years due to advances in coronary reperfusion techniques. However, during the COVID-19 pandemic, there was an unexpected rise in the incidence of post-MI VSD, likely driven by delays in seeking treatment. This study retrospectively analyzed 10 cases of post-MI VSD treated at our hospitals from March 2018 to August 2023, comparing incidence rates across pre-pandemic, pandemic, and post-pandemic periods. The findings revealed a notable increase in VSD cases during the pandemic, with six cases occurring in two years, compared to only two cases in each of the pre-pandemic and post-pandemic periods. Despite these fluctuations, surgical intervention remained a crucial and effective treatment, with 60% of patients surviving the 30-day follow-up. The study underscores the impact of delayed treatment on VSD incidence during the pandemic and highlights the critical need for timely medical intervention to manage severe MI complications effectively.https://doi.org/10.1038/s41598-024-84983-zCOVID-19 pandemicVentricular Setpal defectMyocardial infarctionPost-MI complicationsDelayed treatmentSurgical correction |
| spellingShingle | Giuseppe Nasso Ignazio Condello Walter Vignaroli Andrea Antonazzo Francesco Bartolomucci Barbara Pala Claudio Larosa Annachiara Pingitore Vincenzo Amodeo Vincenzo Montemurro Mizar D’Abramo Roberto Ceravolo Domenica Donato Pasquale Fratto Maria Grazia De Rosis Giuseppe Diaferia Rita Torraco Gaetano Contegiacomo Guido Lembo Mario Siro Brigiani Giuseppe Santarpino Giuseppe Speziale Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic Scientific Reports COVID-19 pandemic Ventricular Setpal defect Myocardial infarction Post-MI complications Delayed treatment Surgical correction |
| title | Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic |
| title_full | Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic |
| title_fullStr | Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic |
| title_full_unstemmed | Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic |
| title_short | Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic |
| title_sort | post myocardial infarction ventricular septal defects incidence and treatment trends during and after the covid 19 pandemic |
| topic | COVID-19 pandemic Ventricular Setpal defect Myocardial infarction Post-MI complications Delayed treatment Surgical correction |
| url | https://doi.org/10.1038/s41598-024-84983-z |
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