Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)

An open controlled study of efficacy and tolerability of a complex drug Calcemin Advance (CA) in osteopenia in postmenopausal women was performed. 100 women (mean age 58,7±4,5 years) were included. They were randomized into 2 groups. 50 pts of group 1 received CA and 50 pts were included in control...

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Main Authors: O A Nikitinskaya, M Y Toroptsova, S G Anikin, T A Korotkova, N V Demin, LA Benevolenskaya
Format: Article
Language:Russian
Published: IMA PRESS LLC 2008-06-01
Series:Научно-практическая ревматология
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Online Access:https://rsp.mediar-press.net/rsp/article/view/800
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author O A Nikitinskaya
M Y Toroptsova
S G Anikin
T A Korotkova
N V Demin
LA Benevolenskaya
author_facet O A Nikitinskaya
M Y Toroptsova
S G Anikin
T A Korotkova
N V Demin
LA Benevolenskaya
author_sort O A Nikitinskaya
collection DOAJ
description An open controlled study of efficacy and tolerability of a complex drug Calcemin Advance (CA) in osteopenia in postmenopausal women was performed. 100 women (mean age 58,7±4,5 years) were included. They were randomized into 2 groups. 50 pts of group 1 received CA and 50 pts were included in control group. Bone mineral density (BMD) analysis after 12 months showed stable BMD in pts receiving CA (0,16±4,19%). In control group BMD decreased in all assessed sites, particularly in lumbar spine (-1,63+4,47%, p=0,013). In this group significant decrease of pain was achieved already after 3 months of treatment and was maintained till the end of the study. CA significantly influenced bone remodeling markers. CA is well tolerated. Adverse events appeared in 10% of pts and did not required drug withdrawal.
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institution Kabale University
issn 1995-4484
1995-4492
language Russian
publishDate 2008-06-01
publisher IMA PRESS LLC
record_format Article
series Научно-практическая ревматология
spelling doaj-art-e1764843648040649b8ab9197839c40f2025-08-20T03:38:11ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922008-06-01463737910.14412/1995-4484-2008-663740Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)O A NikitinskayaM Y ToroptsovaS G AnikinT A KorotkovaN V DeminLA BenevolenskayaAn open controlled study of efficacy and tolerability of a complex drug Calcemin Advance (CA) in osteopenia in postmenopausal women was performed. 100 women (mean age 58,7±4,5 years) were included. They were randomized into 2 groups. 50 pts of group 1 received CA and 50 pts were included in control group. Bone mineral density (BMD) analysis after 12 months showed stable BMD in pts receiving CA (0,16±4,19%). In control group BMD decreased in all assessed sites, particularly in lumbar spine (-1,63+4,47%, p=0,013). In this group significant decrease of pain was achieved already after 3 months of treatment and was maintained till the end of the study. CA significantly influenced bone remodeling markers. CA is well tolerated. Adverse events appeared in 10% of pts and did not required drug withdrawal.https://rsp.mediar-press.net/rsp/article/view/800pmphylaxix of osteoporosisosteopeniacalcemin advance
spellingShingle O A Nikitinskaya
M Y Toroptsova
S G Anikin
T A Korotkova
N V Demin
LA Benevolenskaya
Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)
Научно-практическая ревматология
pmphylaxix of osteoporosis
osteopenia
calcemin advance
title Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)
title_full Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)
title_fullStr Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)
title_full_unstemmed Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)
title_short Prophylaxis of primary osteoporosis in women with complex drug Calcemin Advance (results of an open year’s study)
title_sort prophylaxis of primary osteoporosis in women with complex drug calcemin advance results of an open year s study
topic pmphylaxix of osteoporosis
osteopenia
calcemin advance
url https://rsp.mediar-press.net/rsp/article/view/800
work_keys_str_mv AT oanikitinskaya prophylaxisofprimaryosteoporosisinwomenwithcomplexdrugcalceminadvanceresultsofanopenyearsstudy
AT mytoroptsova prophylaxisofprimaryosteoporosisinwomenwithcomplexdrugcalceminadvanceresultsofanopenyearsstudy
AT sganikin prophylaxisofprimaryosteoporosisinwomenwithcomplexdrugcalceminadvanceresultsofanopenyearsstudy
AT takorotkova prophylaxisofprimaryosteoporosisinwomenwithcomplexdrugcalceminadvanceresultsofanopenyearsstudy
AT nvdemin prophylaxisofprimaryosteoporosisinwomenwithcomplexdrugcalceminadvanceresultsofanopenyearsstudy
AT labenevolenskaya prophylaxisofprimaryosteoporosisinwomenwithcomplexdrugcalceminadvanceresultsofanopenyearsstudy