Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate Cancer

Conclusions: SMI decline occurs during AAP treatment for mHSPC and mCRPC, and is more pronounced in patients over 75 years old and those without previous local treatment. There was no statistically significant association between survival outcomes and SMI decline during AAP therapy.

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Main Authors: Eva Streckova, Jiri Stejskal, Daniela Kuruczova, Adam Svobodnik, Radka Stepanova, Tomas Buchler
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/proc/1468262
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author Eva Streckova
Jiri Stejskal
Daniela Kuruczova
Adam Svobodnik
Radka Stepanova
Tomas Buchler
author_facet Eva Streckova
Jiri Stejskal
Daniela Kuruczova
Adam Svobodnik
Radka Stepanova
Tomas Buchler
author_sort Eva Streckova
collection DOAJ
description Conclusions: SMI decline occurs during AAP treatment for mHSPC and mCRPC, and is more pronounced in patients over 75 years old and those without previous local treatment. There was no statistically significant association between survival outcomes and SMI decline during AAP therapy.
format Article
id doaj-art-e176156f39c4453e80b14f5e368e38cb
institution OA Journals
issn 2090-312X
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Prostate Cancer
spelling doaj-art-e176156f39c4453e80b14f5e368e38cb2025-08-20T02:29:18ZengWileyProstate Cancer2090-312X2025-01-01202510.1155/proc/1468262Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate CancerEva Streckova0Jiri Stejskal1Daniela Kuruczova2Adam Svobodnik3Radka Stepanova4Tomas Buchler5Department of Oncology, Second Faculty of MedicineDepartment of Oncology, First Faculty of MedicineANOVA CRODepartment of Pharmacology, Faculty of MedicineDepartment of Pharmacology, Faculty of MedicineDepartment of Oncology, Second Faculty of MedicineConclusions: SMI decline occurs during AAP treatment for mHSPC and mCRPC, and is more pronounced in patients over 75 years old and those without previous local treatment. There was no statistically significant association between survival outcomes and SMI decline during AAP therapy.http://dx.doi.org/10.1155/proc/1468262
spellingShingle Eva Streckova
Jiri Stejskal
Daniela Kuruczova
Adam Svobodnik
Radka Stepanova
Tomas Buchler
Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate Cancer
Prostate Cancer
title Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate Cancer
title_full Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate Cancer
title_fullStr Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate Cancer
title_full_unstemmed Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate Cancer
title_short Skeletal Muscle Loss During Treatment With Abiraterone in Patients With Metastatic Prostate Cancer
title_sort skeletal muscle loss during treatment with abiraterone in patients with metastatic prostate cancer
url http://dx.doi.org/10.1155/proc/1468262
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AT adamsvobodnik skeletalmusclelossduringtreatmentwithabirateroneinpatientswithmetastaticprostatecancer
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