Sensing of immature particles produced by dengue virus infected cells induces an antiviral response by plasmacytoid dendritic cells.

Dengue virus (DENV) is the leading cause of mosquito-borne viral illness and death in humans. Like many viruses, DENV has evolved potent mechanisms that abolish the antiviral response within infected cells. Nevertheless, several in vivo studies have demonstrated a key role of the innate immune respo...

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Bibliographic Details
Main Authors: Elodie Décembre, Sonia Assil, Marine L B Hillaire, Wanwisa Dejnirattisai, Juthathip Mongkolsapaya, Gavin R Screaton, Andrew D Davidson, Marlène Dreux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004434&type=printable
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