Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis

Abstract Marine sponges host diverse and specialized microbial communities that serve essential functions in nutrient cycling, ecosystem stability, and biotechnological applications. This study investigates the diversity and composition of sponge-associated microbiomes from eight sponge species coll...

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Main Authors: Myoung-Sook Shin, Inho Yang, Weihong Wang, Hiyoung Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-16155-6
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author Myoung-Sook Shin
Inho Yang
Weihong Wang
Hiyoung Kim
author_facet Myoung-Sook Shin
Inho Yang
Weihong Wang
Hiyoung Kim
author_sort Myoung-Sook Shin
collection DOAJ
description Abstract Marine sponges host diverse and specialized microbial communities that serve essential functions in nutrient cycling, ecosystem stability, and biotechnological applications. This study investigates the diversity and composition of sponge-associated microbiomes from eight sponge species collected in Chuksan Harbor, South Korea, using full-length 16S rRNA sequencing and amplicon sequence variant (ASV)-based methods. Our results demonstrate that each sponge species harbors distinct and highly structured microbial communities. Proteobacteria, and especially Alpha- and Gammaproteobacteria, were generally dominant; however, unique dominance patterns, such as the near-exclusive presence of an uncharacterized Gammaproteobacterial lineage in Cliona celata, suggest strong host–symbiont specificity and possible coevolution. Notably, no ASVs were shared between seawater and sponge samples, confirming that sponge hosts select and maintain unique sets of microbial partners. In several Halichondria species, we detected the presence of Entotheonella, a symbiont with high biosynthetic gene cluster diversity that may contribute to host chemical defense and metabolic versatility. Depth-driven differences in microbial community composition were exemplified by Geodia reniformis, whose microbiome was dominated by deep-sea adapted and metabolically versatile lineages such as SAR202, PAUC34f, and Dadabacteriales. This study establishes a new baseline for understanding sponge–microbe partnerships in Korean marine environments. Our integrative, high-resolution approach not only uncovers remarkable taxonomic and functional diversity, but also provides a valuable genetic resource for future marine natural-product discovery and advances ecological restoration efforts.
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spelling doaj-art-e16dd2f060804ed586f61291cb5263b92025-08-20T04:03:18ZengNature PortfolioScientific Reports2045-23222025-08-0115111210.1038/s41598-025-16155-6Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysisMyoung-Sook Shin0Inho Yang1Weihong Wang2Hiyoung Kim3College of Korean Medicine, Gachon UniversityDepartment of Convergence Study on the Ocean Science and Technology, Korea Maritime and Ocean UniversitySchool of Earth and Environmental Sciences, Seoul National UniversityDepartment of Biomedical Science and Engineering, Konkuk UniversityAbstract Marine sponges host diverse and specialized microbial communities that serve essential functions in nutrient cycling, ecosystem stability, and biotechnological applications. This study investigates the diversity and composition of sponge-associated microbiomes from eight sponge species collected in Chuksan Harbor, South Korea, using full-length 16S rRNA sequencing and amplicon sequence variant (ASV)-based methods. Our results demonstrate that each sponge species harbors distinct and highly structured microbial communities. Proteobacteria, and especially Alpha- and Gammaproteobacteria, were generally dominant; however, unique dominance patterns, such as the near-exclusive presence of an uncharacterized Gammaproteobacterial lineage in Cliona celata, suggest strong host–symbiont specificity and possible coevolution. Notably, no ASVs were shared between seawater and sponge samples, confirming that sponge hosts select and maintain unique sets of microbial partners. In several Halichondria species, we detected the presence of Entotheonella, a symbiont with high biosynthetic gene cluster diversity that may contribute to host chemical defense and metabolic versatility. Depth-driven differences in microbial community composition were exemplified by Geodia reniformis, whose microbiome was dominated by deep-sea adapted and metabolically versatile lineages such as SAR202, PAUC34f, and Dadabacteriales. This study establishes a new baseline for understanding sponge–microbe partnerships in Korean marine environments. Our integrative, high-resolution approach not only uncovers remarkable taxonomic and functional diversity, but also provides a valuable genetic resource for future marine natural-product discovery and advances ecological restoration efforts.https://doi.org/10.1038/s41598-025-16155-6Amplicon sequencingFull-length 16S rRNAKorean spongesMicrobial community compositionSponge microbiomeSymbiotic microorganisms
spellingShingle Myoung-Sook Shin
Inho Yang
Weihong Wang
Hiyoung Kim
Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis
Scientific Reports
Amplicon sequencing
Full-length 16S rRNA
Korean sponges
Microbial community composition
Sponge microbiome
Symbiotic microorganisms
title Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis
title_full Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis
title_fullStr Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis
title_full_unstemmed Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis
title_short Diversity and composition of sponge-associated microbiomes from Korean sponges revealed by full-length 16S rRNA analysis
title_sort diversity and composition of sponge associated microbiomes from korean sponges revealed by full length 16s rrna analysis
topic Amplicon sequencing
Full-length 16S rRNA
Korean sponges
Microbial community composition
Sponge microbiome
Symbiotic microorganisms
url https://doi.org/10.1038/s41598-025-16155-6
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