Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens

This experiment aimed to investigate the appropriate level of degossypolized cottonseed protein (DGCP) in the diet of laying hens. A total of 600 49-week-old Lohmann pink laying hens were allocated to five treatments, with six replicates per treatment and 20 birds per replicate. The control group wa...

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Main Authors: Ru Li, Xingyuan Luo, Shiping Bai, Xuemei Ding, Jianping Wang, Qiufeng Zeng, Yue Xuan, Shanshan Li, Sharina Qi, Xiaojuan Bi, Chao He, Xuanming Chen, Keying Zhang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Agriculture
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Online Access:https://www.mdpi.com/2077-0472/15/14/1482
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author Ru Li
Xingyuan Luo
Shiping Bai
Xuemei Ding
Jianping Wang
Qiufeng Zeng
Yue Xuan
Shanshan Li
Sharina Qi
Xiaojuan Bi
Chao He
Xuanming Chen
Keying Zhang
author_facet Ru Li
Xingyuan Luo
Shiping Bai
Xuemei Ding
Jianping Wang
Qiufeng Zeng
Yue Xuan
Shanshan Li
Sharina Qi
Xiaojuan Bi
Chao He
Xuanming Chen
Keying Zhang
author_sort Ru Li
collection DOAJ
description This experiment aimed to investigate the appropriate level of degossypolized cottonseed protein (DGCP) in the diet of laying hens. A total of 600 49-week-old Lohmann pink laying hens were allocated to five treatments, with six replicates per treatment and 20 birds per replicate. The control group was fed a corn-soybean meal basal diet. Four experimental diets were formulated by replacing 25%, 50%, 75%, and 100% of the soybean meal protein-equivalent capacity with DGCP, where 100% replacement corresponded to the maximum safe inclusion of DGCP. The study period lasted for 8 weeks. The results showed that the feed intake, average egg weight, egg mass, laying rate, and the albumen percentage were significantly reduced in the 100% DGCP group (<i>p</i> < 0.05). Plasma uric acid (UA), total cholesterol (TC), triglyceride (TG), and potassium (K) levels were significantly lower (<i>p</i> < 0.05), and depth of crypt (CD) was significantly higher (<i>p</i> < 0.05) in the 100% DGCP group. The DGCP diet linearly increased the relative abundance of Bacteroidota and Bacteroide and significantly increased the relative abundance of Desulfobacterotas in the cecum contents compared to the control group (<i>p</i> < 0.05). The ACE and Chao1 indices in both the control group and the 100% DGCP group were significantly decreased (<i>p</i> < 0.05). In conclusion, the dietary addition of DGCP can reach up to 114.6 g/kg.
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spelling doaj-art-e16db05f1ad34bc28201fce3b7ed87152025-08-20T02:45:52ZengMDPI AGAgriculture2077-04722025-07-011514148210.3390/agriculture15141482Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying HensRu Li0Xingyuan Luo1Shiping Bai2Xuemei Ding3Jianping Wang4Qiufeng Zeng5Yue Xuan6Shanshan Li7Sharina Qi8Xiaojuan Bi9Chao He10Xuanming Chen11Keying Zhang12Animal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaSichuan Sundaily Farm Ecological Food Co., Ltd., Mianyang 622100, ChinaSichuan Sundaily Farm Ecological Food Co., Ltd., Mianyang 622100, ChinaSichuan Sundaily Farm Ecological Food Co., Ltd., Mianyang 622100, ChinaSichuan Sundaily Farm Ecological Food Co., Ltd., Mianyang 622100, ChinaAnimal Nutrition Institute, Key Laboratory for Animal Disease-Resistance Nutrition, Ministry of Education, Ministry of Agriculture and Rural Affairs, Key Laboratory of Sichuan Province, Sichuan Agricultural University, 211 Huimin Road, Wenjiang District, Chengdu 611130, ChinaThis experiment aimed to investigate the appropriate level of degossypolized cottonseed protein (DGCP) in the diet of laying hens. A total of 600 49-week-old Lohmann pink laying hens were allocated to five treatments, with six replicates per treatment and 20 birds per replicate. The control group was fed a corn-soybean meal basal diet. Four experimental diets were formulated by replacing 25%, 50%, 75%, and 100% of the soybean meal protein-equivalent capacity with DGCP, where 100% replacement corresponded to the maximum safe inclusion of DGCP. The study period lasted for 8 weeks. The results showed that the feed intake, average egg weight, egg mass, laying rate, and the albumen percentage were significantly reduced in the 100% DGCP group (<i>p</i> < 0.05). Plasma uric acid (UA), total cholesterol (TC), triglyceride (TG), and potassium (K) levels were significantly lower (<i>p</i> < 0.05), and depth of crypt (CD) was significantly higher (<i>p</i> < 0.05) in the 100% DGCP group. The DGCP diet linearly increased the relative abundance of Bacteroidota and Bacteroide and significantly increased the relative abundance of Desulfobacterotas in the cecum contents compared to the control group (<i>p</i> < 0.05). The ACE and Chao1 indices in both the control group and the 100% DGCP group were significantly decreased (<i>p</i> < 0.05). In conclusion, the dietary addition of DGCP can reach up to 114.6 g/kg.https://www.mdpi.com/2077-0472/15/14/1482degossypolized cottonseed proteinlaying performanceegg qualitygossypol residueblood indexesintestinal health
spellingShingle Ru Li
Xingyuan Luo
Shiping Bai
Xuemei Ding
Jianping Wang
Qiufeng Zeng
Yue Xuan
Shanshan Li
Sharina Qi
Xiaojuan Bi
Chao He
Xuanming Chen
Keying Zhang
Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens
Agriculture
degossypolized cottonseed protein
laying performance
egg quality
gossypol residue
blood indexes
intestinal health
title Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens
title_full Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens
title_fullStr Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens
title_full_unstemmed Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens
title_short Effects of Degossypolized Cottonseed Protein on the Laying Performance, Egg Quality, Blood Indexes, Gossypol Residue, Liver and Uterine Histopathological Changes, and Intestinal Health of Laying Hens
title_sort effects of degossypolized cottonseed protein on the laying performance egg quality blood indexes gossypol residue liver and uterine histopathological changes and intestinal health of laying hens
topic degossypolized cottonseed protein
laying performance
egg quality
gossypol residue
blood indexes
intestinal health
url https://www.mdpi.com/2077-0472/15/14/1482
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