Development and Evaluation of Fluconazole Co-Crystal for Improved Solubility and Mechanical Properties

Development and Evaluation of Fluconazole Co-Crystal for Improved Solubility and Mechanical Properties

<b>Background</b>: Fluconazole (FLZ) is a broad-spectrum anti-fungal drug presenting poor flowability, mechanical properties, and limited aqueous solubility. These issues pose challenges for the handling and manufacturing of dosage forms of FLZ. The current research aimed to develop fluc...

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Bibliographic Details
Main Authors: Ritu Rathi, Inderbir Singh, Tanikan Sangnim, Kampanart Huanbutta
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
co-crystal
antifungal
solubility
tabletability
compaction
compression
Online Access:https://www.mdpi.com/1999-4923/17/3/371
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