Normal tissue transcriptional signatures for tumor-type-agnostic phenotype prediction

Abstract Cancer transcriptional patterns reflect both unique features and shared hallmarks across diverse cancer types, but whether differences in these patterns are sufficient to characterize the full breadth of tumor phenotype heterogeneity remains an open question. We hypothesized that these shar...

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Bibliographic Details
Main Authors: Corey Weistuch, Kevin A. Murgas, Jiening Zhu, Larry Norton, Ken A. Dill, Allen R. Tannenbaum, Joseph O. Deasy
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-76625-1
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