ATF4-mediated expression of NOXA is critical for necroptosis driven by glucose deprivation

ATF4-mediated expression of NOXA is critical for necroptosis driven by glucose deprivation

Glucose deprivation (GD), a common metabolic stress condition, has been recognized as a potent inducer of necroptotic cell death. Our previous findings suggested that the mitochondrial protein, Noxa, may be involved in mediating the release of mitochondrial DNA during GD-induced ZBP1-dependent necro...

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Bibliographic Details
Main Authors: Sasiprapa Sonkaew, Ruwaida Rajna, Yeon-Ji Park, Jiong Yan, Zhaoshan Liu, Siriporn Jitkaew, Zheng-Gang Liu, Swati Choksi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell Death
Subjects:
glucose deprivation
Noxa
ATF4
necroptosis
cell death
Online Access:https://www.frontiersin.org/articles/10.3389/fceld.2024.1507960/full
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