Synthesis of thiosemicarbazone Schiff base derivatives as anti-leishmanial agents and molecular dynamics simulations insights
Abstract Leishmaniasis is one of the infectious diseases caused by protozoa and is considered the second most significant parasitic disease after malaria. In this research, thiosemicarbazone Schiff base derivatives were synthesized via a one-pot, two-step, three-component reaction. Then, the effecti...
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| Main Authors: | Soheila Molaei, Jafar Abbasi Shiran, Neda Shakour, Majid Baradaran, Zahra Malihi, Mohammad Reza Rahimi, Yasamin Abedini Zal, Saghi Sepehri |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-10545-6 |
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