Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase Modulation
In order to break the diffraction limit and improve the imaging resolution of optical microscope, in this article, we theoretically deduced the influence of phase difference on imaging resolution under coherent illumination. As the phase difference increased, the resolution improved gradually. Inspi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-10-01
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| Series: | Optics |
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| Online Access: | https://www.mdpi.com/2673-3269/5/4/30 |
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| author | Jinzhong Ling Yangyang Li Jinkun Guo Xin Liu Xiaorui Wang |
| author_facet | Jinzhong Ling Yangyang Li Jinkun Guo Xin Liu Xiaorui Wang |
| author_sort | Jinzhong Ling |
| collection | DOAJ |
| description | In order to break the diffraction limit and improve the imaging resolution of optical microscope, in this article, we theoretically deduced the influence of phase difference on imaging resolution under coherent illumination. As the phase difference increased, the resolution improved gradually. Inspired by this conclusion, a super-resolution optical imaging system based on phase modulation was proposed and simulated. An optical mask was designed to generate additional phase difference for the adjacent area at the sample’s surface, and the influence of its structural parameters was analyzed numerically. The simulation results preliminarily confirm the feasibility of this scheme, laying the foundation for a more optimal and comprehensive super-resolution imaging scheme. Due to its advantages of high resolution, a wide field of view, and being compatible, this non-fluorescence super-resolution imaging scheme is worthy of further research and application. |
| format | Article |
| id | doaj-art-e15b9a101c3c4cf391036b753e85850e |
| institution | DOAJ |
| issn | 2673-3269 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Optics |
| spelling | doaj-art-e15b9a101c3c4cf391036b753e85850e2025-08-20T02:50:41ZengMDPI AGOptics2673-32692024-10-015440641510.3390/opt5040030Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase ModulationJinzhong Ling0Yangyang Li1Jinkun Guo2Xin Liu3Xiaorui Wang4School of Optoelectronic Engineering, Xidian University, Xi’an 710071, ChinaSchool of Optoelectronic Engineering, Xidian University, Xi’an 710071, ChinaSchool of Optoelectronic Engineering, Xidian University, Xi’an 710071, ChinaSchool of Optoelectronic Engineering, Xidian University, Xi’an 710071, ChinaSchool of Optoelectronic Engineering, Xidian University, Xi’an 710071, ChinaIn order to break the diffraction limit and improve the imaging resolution of optical microscope, in this article, we theoretically deduced the influence of phase difference on imaging resolution under coherent illumination. As the phase difference increased, the resolution improved gradually. Inspired by this conclusion, a super-resolution optical imaging system based on phase modulation was proposed and simulated. An optical mask was designed to generate additional phase difference for the adjacent area at the sample’s surface, and the influence of its structural parameters was analyzed numerically. The simulation results preliminarily confirm the feasibility of this scheme, laying the foundation for a more optimal and comprehensive super-resolution imaging scheme. Due to its advantages of high resolution, a wide field of view, and being compatible, this non-fluorescence super-resolution imaging scheme is worthy of further research and application.https://www.mdpi.com/2673-3269/5/4/30microscopydiffraction limitsuper-resolution imagingphase modulation |
| spellingShingle | Jinzhong Ling Yangyang Li Jinkun Guo Xin Liu Xiaorui Wang Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase Modulation Optics microscopy diffraction limit super-resolution imaging phase modulation |
| title | Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase Modulation |
| title_full | Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase Modulation |
| title_fullStr | Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase Modulation |
| title_full_unstemmed | Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase Modulation |
| title_short | Resolution Improvement for Coherent Illumination Microscopy via Incident Light Phase Modulation |
| title_sort | resolution improvement for coherent illumination microscopy via incident light phase modulation |
| topic | microscopy diffraction limit super-resolution imaging phase modulation |
| url | https://www.mdpi.com/2673-3269/5/4/30 |
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