68Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False Positive
In the detection and characterization of neuroendocrine tumors (NETs), the NETSPOT 68Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) utilizes a somatostatin analog to capture whole body imaging of somatostatin receptors. Here, we report a rare case of incidental coronavirus dis...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2022-06-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750341 |
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| author | Joshua P. Weissman Twyla Bartel |
| author_facet | Joshua P. Weissman Twyla Bartel |
| author_sort | Joshua P. Weissman |
| collection | DOAJ |
| description | In the detection and characterization of neuroendocrine tumors (NETs), the NETSPOT 68Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) utilizes a somatostatin analog to capture whole body imaging of somatostatin receptors. Here, we report a rare case of incidental coronavirus disease 2019 (COVID-19) detection using 68Ga-DOTATATE PET/CT for a 48-year-old patient with COVID-19 who presented to our nuclear medicine department for oncologic and neuroendocrine indications. Current maximal intensity project image from 68Ga-DOTATATE PET/CT demonstrated numerous hypermetabolic foci in the upper abdominal lymph nodes, consistent with somatostatin-avid pancreatic islet cell neoplasm. Radiotracer uptake corresponding to the anatomic infiltrates was also seen in the bilateral pneumonia. With the rise of worldwide COVID-19 cases, and the continued use of NETSPOT for somatostatin avid neoplasms, it is imperative that diagnostic measures of this disease are clearly understood. This case highlights the importance of including COVID-19 on the differential diagnosis when radiotracer uptake appears in 68Ga-DOTATATE PET/CT. |
| format | Article |
| id | doaj-art-e15b70a7eb43492eaf296cfceb3f8afd |
| institution | Kabale University |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-e15b70a7eb43492eaf296cfceb3f8afd2025-08-20T03:48:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122022-06-01210216316510.1055/s-0042-175034168Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False PositiveJoshua P. Weissman0Twyla Bartel1Northwestern University Feinberg School of Medicine, Chicago, Illinois, United StatesGlobal Advanced Imaging, PLLC, Little Rock, Arkansas, United StatesIn the detection and characterization of neuroendocrine tumors (NETs), the NETSPOT 68Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) utilizes a somatostatin analog to capture whole body imaging of somatostatin receptors. Here, we report a rare case of incidental coronavirus disease 2019 (COVID-19) detection using 68Ga-DOTATATE PET/CT for a 48-year-old patient with COVID-19 who presented to our nuclear medicine department for oncologic and neuroendocrine indications. Current maximal intensity project image from 68Ga-DOTATATE PET/CT demonstrated numerous hypermetabolic foci in the upper abdominal lymph nodes, consistent with somatostatin-avid pancreatic islet cell neoplasm. Radiotracer uptake corresponding to the anatomic infiltrates was also seen in the bilateral pneumonia. With the rise of worldwide COVID-19 cases, and the continued use of NETSPOT for somatostatin avid neoplasms, it is imperative that diagnostic measures of this disease are clearly understood. This case highlights the importance of including COVID-19 on the differential diagnosis when radiotracer uptake appears in 68Ga-DOTATATE PET/CT.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750341netspotcoronaviruspet |
| spellingShingle | Joshua P. Weissman Twyla Bartel 68Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False Positive World Journal of Nuclear Medicine netspot coronavirus pet |
| title | 68Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False Positive |
| title_full | 68Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False Positive |
| title_fullStr | 68Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False Positive |
| title_full_unstemmed | 68Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False Positive |
| title_short | 68Ga-DOTATATE Uptake in COVID-19 Pneumonia: A Non-Neoplastic False Positive |
| title_sort | 68ga dotatate uptake in covid 19 pneumonia a non neoplastic false positive |
| topic | netspot coronavirus pet |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1750341 |
| work_keys_str_mv | AT joshuapweissman 68gadotatateuptakeincovid19pneumoniaanonneoplasticfalsepositive AT twylabartel 68gadotatateuptakeincovid19pneumoniaanonneoplasticfalsepositive |