Navigating choice in the face of uncertainty: using a theory informed qualitative approach to identifying potential patient barriers and enablers to participating in an early phase chimeric antigen receptor T (CAR-T) cell therapy trial

Navigating choice in the face of uncertainty: using a theory informed qualitative approach to identifying potential patient barriers and enablers to participating in an early phase chimeric antigen receptor T (CAR-T) cell therapy trial

Objectives Bench to bedside translation of groundbreaking treatments like chimeric antigen receptor T (CAR-T) cell therapy depends on patient participation in early phase trials. Unfortunately, many novel therapies fail to be adequately evaluated due to low recruitment rates, which slows patient acc...

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Main Authors: Dean A Fergusson, Manoj M Lalu, Justin Presseau, Kednapa Thavorn, Joshua Montroy, Natasha Kekre, Gisell Castillo, Sarah Asad, Madison Foster, Terry Hawrysh, Harold Atkins, Stuart Schwartz, Robert A Holt, Raewyn Broady
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/3/e043929.full
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https://bmjopen.bmj.com/content/11/3/e043929.full

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