Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference

The annual ImmunoRad Conference has established itself as a recurrent occasion to explore the possibility of combining radiation therapy (RT) and immunotherapy (IT) for clinical cancer management. Bringing together a number of preclinical and clinical leaders in the fields of radiation oncology, imm...

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Main Authors: Fereshteh Talebi, Fabiana Gregucci, Jalal Ahmed, Nir Ben Chetrit, Brian D. Brown, Timothy A. Chan, Dhan Chand, Julie Constanzo, Sandra Demaria, Dmitry I. Gabrilovich, Encouse Golden, Andrew Godkin, Chandan Guha, Gaorav P. Gupta, Aisha Hasan, Fernanda G. Herrera, Howard Kaufman, Donna Li, Alan A. Melcher, Sierra McDonald, Taha Merghoub, Arta M. Monjazeb, Sébastien Paris, Sean Pitroda, Anguraj Sadanandam, Dörthe Schaue, Laura Santambrogio, Phillippe Szapary, Julien Sage, James W. Welsh, Anna Wilkins, Kristina H. Young, Eric Wennerberg, Laurence Zitvogel, Lorenzo Galluzzi, Eric Deutsch, Silvia C. Formenti
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:OncoImmunology
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Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2025.2507856
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author Fereshteh Talebi
Fabiana Gregucci
Jalal Ahmed
Nir Ben Chetrit
Brian D. Brown
Timothy A. Chan
Dhan Chand
Julie Constanzo
Sandra Demaria
Dmitry I. Gabrilovich
Encouse Golden
Andrew Godkin
Chandan Guha
Gaorav P. Gupta
Aisha Hasan
Fernanda G. Herrera
Howard Kaufman
Donna Li
Alan A. Melcher
Sierra McDonald
Taha Merghoub
Arta M. Monjazeb
Sébastien Paris
Sean Pitroda
Anguraj Sadanandam
Dörthe Schaue
Laura Santambrogio
Phillippe Szapary
Julien Sage
James W. Welsh
Anna Wilkins
Kristina H. Young
Eric Wennerberg
Laurence Zitvogel
Lorenzo Galluzzi
Eric Deutsch
Silvia C. Formenti
author_facet Fereshteh Talebi
Fabiana Gregucci
Jalal Ahmed
Nir Ben Chetrit
Brian D. Brown
Timothy A. Chan
Dhan Chand
Julie Constanzo
Sandra Demaria
Dmitry I. Gabrilovich
Encouse Golden
Andrew Godkin
Chandan Guha
Gaorav P. Gupta
Aisha Hasan
Fernanda G. Herrera
Howard Kaufman
Donna Li
Alan A. Melcher
Sierra McDonald
Taha Merghoub
Arta M. Monjazeb
Sébastien Paris
Sean Pitroda
Anguraj Sadanandam
Dörthe Schaue
Laura Santambrogio
Phillippe Szapary
Julien Sage
James W. Welsh
Anna Wilkins
Kristina H. Young
Eric Wennerberg
Laurence Zitvogel
Lorenzo Galluzzi
Eric Deutsch
Silvia C. Formenti
author_sort Fereshteh Talebi
collection DOAJ
description The annual ImmunoRad Conference has established itself as a recurrent occasion to explore the possibility of combining radiation therapy (RT) and immunotherapy (IT) for clinical cancer management. Bringing together a number of preclinical and clinical leaders in the fields of radiation oncology, immuno-oncology and IT, this annual event fosters indeed essential conversations and fruitful exchanges on how to address existing challenges to expand the therapeutic value of RT-IT combinations. The 8th edition of the ImmunoRad Conference, which has been held in October 2024 at the Weill Cornell Medical College of New York City, highlighted exciting preclinical and clinical advances at the interface between RT and IT, setting the stage for extra progress toward extended benefits for patients with an increasing variety of tumor types. Here, we critically summarize the lines of investigation that have been discussed at the occasion of the 8th Annual ImmunoRad Conference.
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series OncoImmunology
spelling doaj-art-e1500e40ca2344059a6524ff86d409102025-08-20T02:26:18ZengTaylor & Francis GroupOncoImmunology2162-402X2025-12-0114110.1080/2162402X.2025.2507856Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad ConferenceFereshteh Talebi0Fabiana Gregucci1Jalal Ahmed2Nir Ben Chetrit3Brian D. Brown4Timothy A. Chan5Dhan Chand6Julie Constanzo7Sandra Demaria8Dmitry I. Gabrilovich9Encouse Golden10Andrew Godkin11Chandan Guha12Gaorav P. Gupta13Aisha Hasan14Fernanda G. Herrera15Howard Kaufman16Donna Li17Alan A. Melcher18Sierra McDonald19Taha Merghoub20Arta M. Monjazeb21Sébastien Paris22Sean Pitroda23Anguraj Sadanandam24Dörthe Schaue25Laura Santambrogio26Phillippe Szapary27Julien Sage28James W. Welsh29Anna Wilkins30Kristina H. Young31Eric Wennerberg32Laurence Zitvogel33Lorenzo Galluzzi34Eric Deutsch35Silvia C. Formenti36Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USADepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY, USAIcahn Genomics Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY, USAIcahn Genomics Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Cancer Sciences, Global Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USAAgenus Inc, Lexingston, MA, USAInstitut de Recherche en Cancérologie de Montpellier (IRCM), INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier (ICM), Montpellier, FranceDepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY, USAAstraZeneca, Gaithersburg, MD, USADepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY, USADivision of Infection and Immunity/Systems Immunity University Research Institute, School of Medicine, Cardiff University, Cardiff, UKDepartments of Radiation Oncology and Pathology, Albert Einstein College of Medicine, New York, NY, USADepartment of Radiation Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAJohnson & Johnson, New Brunswick, NJ, USAAGORA Cancer Research Center, Swiss Cancer Center Leman, Lausanne, SwitzerlandAnkyra Therapeutics, Cambridge, MA, USAUniversity of Wisconsin, Madison, WI, USADivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, UKUNC Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USASwim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Weill Cornell Medicine, New York, NY, USADepartment of Radiation Oncology, University of California, San Diego, CA, USANanobiotix, Paris, FranceDepartment of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, University of Chicago, Chicago, IL, USADivision of Molecular Pathology, The Institute of Cancer Research, London, UKDepartment of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USADepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY, USAInterventional Oncology, Johnson & Johnson, New Brunswick, NJDepartments of Genetics and Pediatrics, Stanford University, Stanford, CaliforniaDepartment of Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USADivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, UKDivision of Radiation Oncology, The Oregon Clinic, Portland, OR, USADivision of Radiotherapy and Imaging, The Institute of Cancer Research, London, UKGustave Roussy, INSERM U1015, Division of Medicine, Paris-Saclay University, Center of Clinical Investigations BIOTHERIS, Villejuif, FranceCancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA, USADepartment of Radiation Oncology, Gustave Roussy, INSERM U1030, Division of Medicine, Paris-Saclay University, RHU LySAIRI “Lymphocyte-Sparing Artificial Intelligence-guided Radio-Immunotherapy”, Villejuif, FranceDepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY, USAThe annual ImmunoRad Conference has established itself as a recurrent occasion to explore the possibility of combining radiation therapy (RT) and immunotherapy (IT) for clinical cancer management. Bringing together a number of preclinical and clinical leaders in the fields of radiation oncology, immuno-oncology and IT, this annual event fosters indeed essential conversations and fruitful exchanges on how to address existing challenges to expand the therapeutic value of RT-IT combinations. The 8th edition of the ImmunoRad Conference, which has been held in October 2024 at the Weill Cornell Medical College of New York City, highlighted exciting preclinical and clinical advances at the interface between RT and IT, setting the stage for extra progress toward extended benefits for patients with an increasing variety of tumor types. Here, we critically summarize the lines of investigation that have been discussed at the occasion of the 8th Annual ImmunoRad Conference.https://www.tandfonline.com/doi/10.1080/2162402X.2025.2507856Abscopal effectCAR T cellsCD8+ cytotoxic T lymphocyteslow-dose radiation therapyTREG cellstumor-associated macrophages
spellingShingle Fereshteh Talebi
Fabiana Gregucci
Jalal Ahmed
Nir Ben Chetrit
Brian D. Brown
Timothy A. Chan
Dhan Chand
Julie Constanzo
Sandra Demaria
Dmitry I. Gabrilovich
Encouse Golden
Andrew Godkin
Chandan Guha
Gaorav P. Gupta
Aisha Hasan
Fernanda G. Herrera
Howard Kaufman
Donna Li
Alan A. Melcher
Sierra McDonald
Taha Merghoub
Arta M. Monjazeb
Sébastien Paris
Sean Pitroda
Anguraj Sadanandam
Dörthe Schaue
Laura Santambrogio
Phillippe Szapary
Julien Sage
James W. Welsh
Anna Wilkins
Kristina H. Young
Eric Wennerberg
Laurence Zitvogel
Lorenzo Galluzzi
Eric Deutsch
Silvia C. Formenti
Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference
OncoImmunology
Abscopal effect
CAR T cells
CD8+ cytotoxic T lymphocytes
low-dose radiation therapy
TREG cells
tumor-associated macrophages
title Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference
title_full Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference
title_fullStr Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference
title_full_unstemmed Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference
title_short Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference
title_sort updates on radiotherapy immunotherapy combinations proceedings of 8th annual immunorad conference
topic Abscopal effect
CAR T cells
CD8+ cytotoxic T lymphocytes
low-dose radiation therapy
TREG cells
tumor-associated macrophages
url https://www.tandfonline.com/doi/10.1080/2162402X.2025.2507856
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