LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSIS
Introduction. Over the past few decades in Russia and other countries there has been signifi cant progress in the development of liver transplantation in children. It became possible to operate recipients with very low body mass, to perform transplant from cadaveric and living donors with incompatib...
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2014-09-01
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| Series: | Вестник трансплантологии и искусственных органов |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/448 |
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| author | S. V. Gautier O. M. Tsiroulnikova Y. G. Moysyuk D. G. Akhaladze I. E. Tsiroulnikova O. V. Silina Kh. M. Khizroev A. R. Monakhov E. V. Chekletsova V. A. Pets V. N. Poptsov |
| author_facet | S. V. Gautier O. M. Tsiroulnikova Y. G. Moysyuk D. G. Akhaladze I. E. Tsiroulnikova O. V. Silina Kh. M. Khizroev A. R. Monakhov E. V. Chekletsova V. A. Pets V. N. Poptsov |
| author_sort | S. V. Gautier |
| collection | DOAJ |
| description | Introduction. Over the past few decades in Russia and other countries there has been signifi cant progress in the development of liver transplantation in children. It became possible to operate recipients with very low body mass, to perform transplant from cadaveric and living donors with incompatible blood type, as well as to perform single-step transplantation of liver with kidney or pancreas in patients with combined diseases.Aim: to investigate the 6-year experience of liver transplantation in children in V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs.Materials and methods. From May 2008 to June 2014 304 liver transplantswere performed in 297 children aged from 3 months to 17 years with body mass 4 to 32 kg. 241 living donor liver left lateral section transplants (including 2 in conjunction with kidney), 8 left lobe (including 1 in conjunction with kidney), 40 right lobe liver transplants (including 1 in conjunction with kidney), and 9 cadaveric whole liver transplants (including 1 case of simultaneous liver and pancreas transplantation) and 6 split liver transplants (4 – split left lateral section transplantations and 2 extended right lobe liver grafts) were achieved.41 of these patients received a graft from AB0 – incompatible donors.Results. A retrospective evaluation of surgical technique and analysis of results were carried out. Early mortality was 8.1%, 1-year survival rate – 86.4%, 5-year survival rate – 78.8%.Conclusion. These results suggest the prospects of this procedure for pediatrictransplantation and require further investigation and promotion approaches in medical and social public. |
| format | Article |
| id | doaj-art-e149e0294f5f4e6b975e25f963b7f97c |
| institution | Kabale University |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2014-09-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-e149e0294f5f4e6b975e25f963b7f97c2025-08-20T03:59:53ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912014-09-01163546210.15825/1995-1191-2014-3-54-62390LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSISS. V. Gautier0O. M. Tsiroulnikova1Y. G. Moysyuk2D. G. Akhaladze3I. E. Tsiroulnikova4O. V. Silina5Kh. M. Khizroev6A. R. Monakhov7E. V. Chekletsova8V. A. Pets9V. N. Poptsov10V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationIntroduction. Over the past few decades in Russia and other countries there has been signifi cant progress in the development of liver transplantation in children. It became possible to operate recipients with very low body mass, to perform transplant from cadaveric and living donors with incompatible blood type, as well as to perform single-step transplantation of liver with kidney or pancreas in patients with combined diseases.Aim: to investigate the 6-year experience of liver transplantation in children in V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs.Materials and methods. From May 2008 to June 2014 304 liver transplantswere performed in 297 children aged from 3 months to 17 years with body mass 4 to 32 kg. 241 living donor liver left lateral section transplants (including 2 in conjunction with kidney), 8 left lobe (including 1 in conjunction with kidney), 40 right lobe liver transplants (including 1 in conjunction with kidney), and 9 cadaveric whole liver transplants (including 1 case of simultaneous liver and pancreas transplantation) and 6 split liver transplants (4 – split left lateral section transplantations and 2 extended right lobe liver grafts) were achieved.41 of these patients received a graft from AB0 – incompatible donors.Results. A retrospective evaluation of surgical technique and analysis of results were carried out. Early mortality was 8.1%, 1-year survival rate – 86.4%, 5-year survival rate – 78.8%.Conclusion. These results suggest the prospects of this procedure for pediatrictransplantation and require further investigation and promotion approaches in medical and social public.https://journal.transpl.ru/vtio/article/view/448liver transplantation in childrenleft lateral sectionleft loberight lobewhole liver transplantationliving donor of partial liver graftliver transplantation outcomes |
| spellingShingle | S. V. Gautier O. M. Tsiroulnikova Y. G. Moysyuk D. G. Akhaladze I. E. Tsiroulnikova O. V. Silina Kh. M. Khizroev A. R. Monakhov E. V. Chekletsova V. A. Pets V. N. Poptsov LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSIS Вестник трансплантологии и искусственных органов liver transplantation in children left lateral section left lobe right lobe whole liver transplantation living donor of partial liver graft liver transplantation outcomes |
| title | LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSIS |
| title_full | LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSIS |
| title_fullStr | LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSIS |
| title_full_unstemmed | LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSIS |
| title_short | LIVER TRANSPLANTATION IN CHILDREN: SIX-YEAR EXPERIENCE ANALYSIS |
| title_sort | liver transplantation in children six year experience analysis |
| topic | liver transplantation in children left lateral section left lobe right lobe whole liver transplantation living donor of partial liver graft liver transplantation outcomes |
| url | https://journal.transpl.ru/vtio/article/view/448 |
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