Reactive oxygen species: Janus-faced molecules in the era of modern cancer therapy
Oxidative stress, that is, an unbalanced increase in reactive oxygen species (ROS), contributes to tumor-induced immune suppression and limits the efficacy of immunotherapy. Cancer cells have inherently increased ROS production, intracellularly through metabolic perturbations and extracellularly thr...
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| Main Authors: | Rolf Kiessling, Elias S J Arnér, Aine O’Reilly, Wenchao Zhao, Stina Wickström |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2024-12-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/12/12/e009409.full |
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