Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong Chinese
Purpose. To evaluate the efficacy of using topical cyclosporin A 0.05% (Restasis) for the treatment of paediatric allergic conjunctivitis. Methods. This retrospective study included consecutive cases of paediatric allergic conjunctivitis treated with Restasis between 2010 and 2013. Subjects with fol...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/396987 |
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| author | Macy M. S. Wu Gordon S. K. Yau Jacky W. Y. Lee Amy L. Wong Victor T. Y. Tam Can Y. F. Yuen |
| author_facet | Macy M. S. Wu Gordon S. K. Yau Jacky W. Y. Lee Amy L. Wong Victor T. Y. Tam Can Y. F. Yuen |
| author_sort | Macy M. S. Wu |
| collection | DOAJ |
| description | Purpose. To evaluate the efficacy of using topical cyclosporin A 0.05% (Restasis) for the treatment of paediatric allergic conjunctivitis. Methods. This retrospective study included consecutive cases of paediatric allergic conjunctivitis treated with Restasis between 2010 and 2013. Subjects with follow-up time less than 3 months after using Restasis were excluded. Itch severity score, symptom score, and sign score were compared before (baseline) and 3 months after using Restasis. Results. In 27 eyes of 14 patients (mean age 10.8±3.2 years), 44.4% had allergic conjunctivitis, 33.3% had vernal keratoconjunctivitis, and 22.2% had atopic keratoconjunctivitis. The mean duration of ocular symptoms was 20.4±13.2 months. 92.6% of subjects were using steroid eye drop before Restasis. After 3 months of topical Restasis, there were statistically significant reductions in the symptom, sign, and itch severity scores compared with baseline (all P≤0.001) and 78.6% of subjects were able to be tapered off steroid eye drops.
Conclusion. Topical Restasis was effective and safe in significantly reducing ocular itchiness, sign, and symptom scores at 3 months after use in paediatric allergic ocular conditions. |
| format | Article |
| id | doaj-art-e1487912825a4c1fbfbffa91bb64db58 |
| institution | DOAJ |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-e1487912825a4c1fbfbffa91bb64db582025-08-20T03:21:05ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/396987396987Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong ChineseMacy M. S. Wu0Gordon S. K. Yau1Jacky W. Y. Lee2Amy L. Wong3Victor T. Y. Tam4Can Y. F. Yuen5Department of Ophthalmology, Caritas Medical Center, 111 Wing Hong Street, Kowloon, Hong KongDepartment of Ophthalmology, Caritas Medical Center, 111 Wing Hong Street, Kowloon, Hong KongDepartment of Ophthalmology, Caritas Medical Center, 111 Wing Hong Street, Kowloon, Hong KongDepartment of Ophthalmology, Caritas Medical Center, 111 Wing Hong Street, Kowloon, Hong KongDepartment of Ophthalmology, Caritas Medical Center, 111 Wing Hong Street, Kowloon, Hong KongDepartment of Ophthalmology, Caritas Medical Center, 111 Wing Hong Street, Kowloon, Hong KongPurpose. To evaluate the efficacy of using topical cyclosporin A 0.05% (Restasis) for the treatment of paediatric allergic conjunctivitis. Methods. This retrospective study included consecutive cases of paediatric allergic conjunctivitis treated with Restasis between 2010 and 2013. Subjects with follow-up time less than 3 months after using Restasis were excluded. Itch severity score, symptom score, and sign score were compared before (baseline) and 3 months after using Restasis. Results. In 27 eyes of 14 patients (mean age 10.8±3.2 years), 44.4% had allergic conjunctivitis, 33.3% had vernal keratoconjunctivitis, and 22.2% had atopic keratoconjunctivitis. The mean duration of ocular symptoms was 20.4±13.2 months. 92.6% of subjects were using steroid eye drop before Restasis. After 3 months of topical Restasis, there were statistically significant reductions in the symptom, sign, and itch severity scores compared with baseline (all P≤0.001) and 78.6% of subjects were able to be tapered off steroid eye drops. Conclusion. Topical Restasis was effective and safe in significantly reducing ocular itchiness, sign, and symptom scores at 3 months after use in paediatric allergic ocular conditions.http://dx.doi.org/10.1155/2014/396987 |
| spellingShingle | Macy M. S. Wu Gordon S. K. Yau Jacky W. Y. Lee Amy L. Wong Victor T. Y. Tam Can Y. F. Yuen Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong Chinese The Scientific World Journal |
| title | Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong Chinese |
| title_full | Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong Chinese |
| title_fullStr | Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong Chinese |
| title_full_unstemmed | Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong Chinese |
| title_short | Retrospective Review on the Use of Topical Cyclosporin A 0.05% for Paediatric Allergic Conjunctivitis in Hong Kong Chinese |
| title_sort | retrospective review on the use of topical cyclosporin a 0 05 for paediatric allergic conjunctivitis in hong kong chinese |
| url | http://dx.doi.org/10.1155/2014/396987 |
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