Leukocytosis of Unknown Origin: Gangrenous Cholecystitis

There have been case reports where patients admitted with acute cholecystitis, who were managed conservatively, had subsequently developed GC (gangrenous cholecystitis). The current case is unique, since our patient denied any prior episodes of abdominal pain and the only tip off was leukocytosis. A...

Full description

Saved in:
Bibliographic Details
Main Authors: Amara Jyothi Nidimusili, M. Chadi Alraies, Naseem Eisa, Abdul Hamid Alraiyes, Khaldoon Shaheen
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/418014
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850168250613104640
author Amara Jyothi Nidimusili
M. Chadi Alraies
Naseem Eisa
Abdul Hamid Alraiyes
Khaldoon Shaheen
author_facet Amara Jyothi Nidimusili
M. Chadi Alraies
Naseem Eisa
Abdul Hamid Alraiyes
Khaldoon Shaheen
author_sort Amara Jyothi Nidimusili
collection DOAJ
description There have been case reports where patients admitted with acute cholecystitis, who were managed conservatively, had subsequently developed GC (gangrenous cholecystitis). The current case is unique, since our patient denied any prior episodes of abdominal pain and the only tip off was leukocytosis. A high index of suspicion is essential for the early diagnosis and treatment of GC. GC has a mortality rate of up to 22% and a complication rate of 16–25%. Complications associated with GC include perforation, which has been reported to occur in as many as 10% of cases of acute cholecystitis. The radiological investigations may not be conclusive. Ultrasonography usually serves as the first-line imaging modality for the evaluation of patients with clinically suspected acute cholecystitis. However, CT can play an important role in the evaluation of these patients if sonography is inconclusive. There is a need for an early (if not urgent) surgical intervention in acute cholecystitis (whether laparoscopic or open surgery) in order to decrease the time elapsed from the start of symptoms to admission and treatment.
format Article
id doaj-art-e1481163c22b467385729bf7a696afc6
institution OA Journals
issn 1687-9627
1687-9635
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-e1481163c22b467385729bf7a696afc62025-08-20T02:21:01ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/418014418014Leukocytosis of Unknown Origin: Gangrenous CholecystitisAmara Jyothi Nidimusili0M. Chadi Alraies1Naseem Eisa2Abdul Hamid Alraiyes3Khaldoon Shaheen4Department of Medicine, Trinitas Regional Medical Center, Seton Hall University Health Sciences, Elizabeth, NJ 07202, USADepartment of Hospital Medicine, Institute of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Hospital Medicine, Institute of Medicine, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Pulmonary, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USADepartment of Hospital Medicine, Institute of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, OH 44195, USAThere have been case reports where patients admitted with acute cholecystitis, who were managed conservatively, had subsequently developed GC (gangrenous cholecystitis). The current case is unique, since our patient denied any prior episodes of abdominal pain and the only tip off was leukocytosis. A high index of suspicion is essential for the early diagnosis and treatment of GC. GC has a mortality rate of up to 22% and a complication rate of 16–25%. Complications associated with GC include perforation, which has been reported to occur in as many as 10% of cases of acute cholecystitis. The radiological investigations may not be conclusive. Ultrasonography usually serves as the first-line imaging modality for the evaluation of patients with clinically suspected acute cholecystitis. However, CT can play an important role in the evaluation of these patients if sonography is inconclusive. There is a need for an early (if not urgent) surgical intervention in acute cholecystitis (whether laparoscopic or open surgery) in order to decrease the time elapsed from the start of symptoms to admission and treatment.http://dx.doi.org/10.1155/2013/418014
spellingShingle Amara Jyothi Nidimusili
M. Chadi Alraies
Naseem Eisa
Abdul Hamid Alraiyes
Khaldoon Shaheen
Leukocytosis of Unknown Origin: Gangrenous Cholecystitis
Case Reports in Medicine
title Leukocytosis of Unknown Origin: Gangrenous Cholecystitis
title_full Leukocytosis of Unknown Origin: Gangrenous Cholecystitis
title_fullStr Leukocytosis of Unknown Origin: Gangrenous Cholecystitis
title_full_unstemmed Leukocytosis of Unknown Origin: Gangrenous Cholecystitis
title_short Leukocytosis of Unknown Origin: Gangrenous Cholecystitis
title_sort leukocytosis of unknown origin gangrenous cholecystitis
url http://dx.doi.org/10.1155/2013/418014
work_keys_str_mv AT amarajyothinidimusili leukocytosisofunknownorigingangrenouscholecystitis
AT mchadialraies leukocytosisofunknownorigingangrenouscholecystitis
AT naseemeisa leukocytosisofunknownorigingangrenouscholecystitis
AT abdulhamidalraiyes leukocytosisofunknownorigingangrenouscholecystitis
AT khaldoonshaheen leukocytosisofunknownorigingangrenouscholecystitis