Early childhood weight trajectory differences in twins, singletons, and gestational-age matched singletons
Objective: Understanding of twin growth in the United States (US) is based on outdated or predominantly non-Hispanic White samples, and the age at which twins catch up to singletons is unclear. In this study, we characterized normative weight trajectories of twins and singletons in a contemporary, d...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
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| Series: | Preventive Medicine Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211335525000233 |
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| Summary: | Objective: Understanding of twin growth in the United States (US) is based on outdated or predominantly non-Hispanic White samples, and the age at which twins catch up to singletons is unclear. In this study, we characterized normative weight trajectories of twins and singletons in a contemporary, diverse cohort. Methods: Data were from the PROMISE study, an electronic health record-based cohort of pregnant people and their children in the US (2005–2021). The Jenss model was used to characterize weight trajectories from 0 to 24 months of age. Twins (n = 716) were compared to the full cohort of singletons (n = 40,075) and a matched sample with similar gestational age at birth (GA) (n = 7160). Results: Male and female twins had lower birth weight compared to singletons and experienced a high rate of weight gain throughout infancy. Among males, twins caught up in weight to the full singleton cohort and to GA-matched singletons at approximately 12 and 6 months, respectively. Among females, twins caught up to GA-matched singletons at approximately 15 months but did not fully overcome their birth weight disadvantage to the full singleton sample by 24 months. Conclusions: These findings highlight that the use of singleton growth charts or preterm singleton growth charts among twins may be inappropriate and suggest the need for a twin-specific growth chart. Future research is needed to understand factors that drive differences in weight trajectories between twins and singletons and to guide twin-specific guidelines. |
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| ISSN: | 2211-3355 |