In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review

Acute pancreatitis is one of the severe complications of hypertriglyceridemia, which needs to be recognized early to provide appropriate treatment. Hypertriglyceridemia-induced pancreatitis has several causes, in which in vitro fertilization (IVF) is a rare etiology that is becoming increasingly pop...

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Main Authors: Nguyen Huu Thanh, Trinh Van Duong, Nguyen Thu Huyen, Pham Dang Hai
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-10-01
Series:Turkish Journal of Emergency Medicine
Subjects:
Online Access:https://journals.lww.com/10.4103/tjem.tjem_27_24
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author Nguyen Huu Thanh
Trinh Van Duong
Nguyen Thu Huyen
Pham Dang Hai
author_facet Nguyen Huu Thanh
Trinh Van Duong
Nguyen Thu Huyen
Pham Dang Hai
author_sort Nguyen Huu Thanh
collection DOAJ
description Acute pancreatitis is one of the severe complications of hypertriglyceridemia, which needs to be recognized early to provide appropriate treatment. Hypertriglyceridemia-induced pancreatitis has several causes, in which in vitro fertilization (IVF) is a rare etiology that is becoming increasingly popular. We report a 33-year-old female patient with a history of hypertension who has failed an IVF cycle and started a new IVF procedure 1 month before admission. She was diagnosed with severe triglyceridemia-induced acute pancreatitis with extremely high serum triglycerides (TGs) levels (18,547 mg/dL). We combined plasmapheresis and intravenous (IV) insulin and significantly reduced blood TG over a short time. She was discharged with a TG level of 366.7 mg/dL on the 10th day. It is essential to monitor serum TG levels in plasma before, during, and after this therapy, especially in the 1st month after initiating IVF. Although plasmapheresis combined with IV insulin is not officially recommended for acute triglyceridemia-induced pancreatitis, the therapy can be considered in cases with extremely high serum TG levels.
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spelling doaj-art-e13d25748fe1438590898d609718b5082025-08-20T02:14:20ZengWolters Kluwer Medknow PublicationsTurkish Journal of Emergency Medicine2452-24732024-10-0124425525810.4103/tjem.tjem_27_24In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature reviewNguyen Huu ThanhTrinh Van DuongNguyen Thu HuyenPham Dang HaiAcute pancreatitis is one of the severe complications of hypertriglyceridemia, which needs to be recognized early to provide appropriate treatment. Hypertriglyceridemia-induced pancreatitis has several causes, in which in vitro fertilization (IVF) is a rare etiology that is becoming increasingly popular. We report a 33-year-old female patient with a history of hypertension who has failed an IVF cycle and started a new IVF procedure 1 month before admission. She was diagnosed with severe triglyceridemia-induced acute pancreatitis with extremely high serum triglycerides (TGs) levels (18,547 mg/dL). We combined plasmapheresis and intravenous (IV) insulin and significantly reduced blood TG over a short time. She was discharged with a TG level of 366.7 mg/dL on the 10th day. It is essential to monitor serum TG levels in plasma before, during, and after this therapy, especially in the 1st month after initiating IVF. Although plasmapheresis combined with IV insulin is not officially recommended for acute triglyceridemia-induced pancreatitis, the therapy can be considered in cases with extremely high serum TG levels.https://journals.lww.com/10.4103/tjem.tjem_27_24acute pancreatitisestrogenhypertriglyceridein vitro fertilization
spellingShingle Nguyen Huu Thanh
Trinh Van Duong
Nguyen Thu Huyen
Pham Dang Hai
In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review
Turkish Journal of Emergency Medicine
acute pancreatitis
estrogen
hypertriglyceride
in vitro fertilization
title In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review
title_full In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review
title_fullStr In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review
title_full_unstemmed In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review
title_short In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review
title_sort in vitro fertilization induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department a case report and literature review
topic acute pancreatitis
estrogen
hypertriglyceride
in vitro fertilization
url https://journals.lww.com/10.4103/tjem.tjem_27_24
work_keys_str_mv AT nguyenhuuthanh invitrofertilizationinducedextremehypertriglyceridemiawithsecondaryacutepancreatitisinemergencydepartmentacasereportandliteraturereview
AT trinhvanduong invitrofertilizationinducedextremehypertriglyceridemiawithsecondaryacutepancreatitisinemergencydepartmentacasereportandliteraturereview
AT nguyenthuhuyen invitrofertilizationinducedextremehypertriglyceridemiawithsecondaryacutepancreatitisinemergencydepartmentacasereportandliteraturereview
AT phamdanghai invitrofertilizationinducedextremehypertriglyceridemiawithsecondaryacutepancreatitisinemergencydepartmentacasereportandliteraturereview