Human herpesvirus 6 infection mimicking measles: two pediatric cases

Measles is a highly contagious viral infection associated with clinical symptoms such as fever, cough, conjunctivitis, coryza, eruption and increased serum immunoglobulin M (IgM) antibodies. A clinical diagnosis is easily established when the chain of infection can be followed. However, Japan...

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Main Authors: Masahide Goto, Hideki Kumagai, Ryou Kawamata, Shizuko Matsumoto, Miki Watanabe, Yasuyuki Nozaki
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2015-02-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/1194
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author Masahide Goto
Hideki Kumagai
Ryou Kawamata
Shizuko Matsumoto
Miki Watanabe
Yasuyuki Nozaki
author_facet Masahide Goto
Hideki Kumagai
Ryou Kawamata
Shizuko Matsumoto
Miki Watanabe
Yasuyuki Nozaki
author_sort Masahide Goto
collection DOAJ
description Measles is a highly contagious viral infection associated with clinical symptoms such as fever, cough, conjunctivitis, coryza, eruption and increased serum immunoglobulin M (IgM) antibodies. A clinical diagnosis is easily established when the chain of infection can be followed. However, Japan is currently experiencing sporadic measles outbreaks, which complicate the establishment of diagnosis. Furthermore, other exanthematous infections such as rubella, human parvovirus B19, human herpesvirus 6 (HHV-6) and HHV-7 present with clinical symptoms and IgM antibody levels similar to those in measles. Therefore, real-time polymerase chain reaction virogene testing has been part of Japan's standard diagnostic protocol for measles since 2010. This report presents two pediatric cases clinically resembling measles that were diagnosed as HHV-6 based on a virogene detection test. This underscores the importance of performing pathogen testing to confirm a diagnosis when measles is suspected.
format Article
id doaj-art-e131028673eb4ca480cb56c55f032f9c
institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 2015-02-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-e131028673eb4ca480cb56c55f032f9c2025-08-20T03:01:11ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212015-02-01571Human herpesvirus 6 infection mimicking measles: two pediatric casesMasahide Goto0Hideki KumagaiRyou KawamataShizuko MatsumotoMiki WatanabeYasuyuki NozakiDepartment of Pediatrics, Hitachiomiya Saiseikai Hospital, Ibaraki Prefectural Institute of Public Health, Ibaraki, Japan. masapon.go@gmail.com. Measles is a highly contagious viral infection associated with clinical symptoms such as fever, cough, conjunctivitis, coryza, eruption and increased serum immunoglobulin M (IgM) antibodies. A clinical diagnosis is easily established when the chain of infection can be followed. However, Japan is currently experiencing sporadic measles outbreaks, which complicate the establishment of diagnosis. Furthermore, other exanthematous infections such as rubella, human parvovirus B19, human herpesvirus 6 (HHV-6) and HHV-7 present with clinical symptoms and IgM antibody levels similar to those in measles. Therefore, real-time polymerase chain reaction virogene testing has been part of Japan's standard diagnostic protocol for measles since 2010. This report presents two pediatric cases clinically resembling measles that were diagnosed as HHV-6 based on a virogene detection test. This underscores the importance of performing pathogen testing to confirm a diagnosis when measles is suspected. https://turkjpediatr.org/article/view/1194
spellingShingle Masahide Goto
Hideki Kumagai
Ryou Kawamata
Shizuko Matsumoto
Miki Watanabe
Yasuyuki Nozaki
Human herpesvirus 6 infection mimicking measles: two pediatric cases
The Turkish Journal of Pediatrics
title Human herpesvirus 6 infection mimicking measles: two pediatric cases
title_full Human herpesvirus 6 infection mimicking measles: two pediatric cases
title_fullStr Human herpesvirus 6 infection mimicking measles: two pediatric cases
title_full_unstemmed Human herpesvirus 6 infection mimicking measles: two pediatric cases
title_short Human herpesvirus 6 infection mimicking measles: two pediatric cases
title_sort human herpesvirus 6 infection mimicking measles two pediatric cases
url https://turkjpediatr.org/article/view/1194
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