Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDT
Wide local excision with a 1 cm margin is the standard treatment for proliferating trichilemmal tumor (PTT), but it is challenging to treat giant tumors, or tumors located on the scalp and face. We present a case of a 90-year-old woman with painful PTT on the cheek who was cured by a combination of...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100023005975 |
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| author | Caihe Liao Mingshun Wu Yeqiang Liu Xiuli Wang Guolong Zhang |
| author_facet | Caihe Liao Mingshun Wu Yeqiang Liu Xiuli Wang Guolong Zhang |
| author_sort | Caihe Liao |
| collection | DOAJ |
| description | Wide local excision with a 1 cm margin is the standard treatment for proliferating trichilemmal tumor (PTT), but it is challenging to treat giant tumors, or tumors located on the scalp and face. We present a case of a 90-year-old woman with painful PTT on the cheek who was cured by a combination of limited resection and neoadjuvant ALA-PDT. Preoperative and postoperative 20 % ALA-PDT was used for a total of 6 sessions. PTT was resected 2 mm outside the clinical margins under local infiltration anesthesia. The PTT with a size of 69 × 59 × 37 mm was removed by limited resection. ALA-PDT was an effective therapy for local anti-inflammation and anti-tumor. The old woman received it well and recovered quickly. Limited resection combined with neoadjuvant ALA-PDT is an advanced treatment for giant PTT, which has the advantages of minimally invasive, effective and safe. |
| format | Article |
| id | doaj-art-e12ba76c1f634a6598cc780a17e46d7f |
| institution | OA Journals |
| issn | 1572-1000 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-e12ba76c1f634a6598cc780a17e46d7f2025-08-20T01:54:51ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-02-014510387010.1016/j.pdpdt.2023.103870Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDTCaihe Liao0Mingshun Wu1Yeqiang Liu2Xiuli Wang3Guolong Zhang4Department of Phototherapy at Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, ChinaDepartment of Phototherapy at Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, ChinaDepartment of Pathology at Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, ChinaDepartment of Phototherapy at Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, China; Corresponding authors.Department of Phototherapy at Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai 200443, China; Corresponding authors.Wide local excision with a 1 cm margin is the standard treatment for proliferating trichilemmal tumor (PTT), but it is challenging to treat giant tumors, or tumors located on the scalp and face. We present a case of a 90-year-old woman with painful PTT on the cheek who was cured by a combination of limited resection and neoadjuvant ALA-PDT. Preoperative and postoperative 20 % ALA-PDT was used for a total of 6 sessions. PTT was resected 2 mm outside the clinical margins under local infiltration anesthesia. The PTT with a size of 69 × 59 × 37 mm was removed by limited resection. ALA-PDT was an effective therapy for local anti-inflammation and anti-tumor. The old woman received it well and recovered quickly. Limited resection combined with neoadjuvant ALA-PDT is an advanced treatment for giant PTT, which has the advantages of minimally invasive, effective and safe.http://www.sciencedirect.com/science/article/pii/S1572100023005975Proliferating trichilemmal tumorNeoadjuvant ALA-PDTLimited resectionPhotodynamic Therapy |
| spellingShingle | Caihe Liao Mingshun Wu Yeqiang Liu Xiuli Wang Guolong Zhang Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDT Photodiagnosis and Photodynamic Therapy Proliferating trichilemmal tumor Neoadjuvant ALA-PDT Limited resection Photodynamic Therapy |
| title | Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDT |
| title_full | Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDT |
| title_fullStr | Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDT |
| title_full_unstemmed | Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDT |
| title_short | Advanced treatment of giant proliferating trichilemmal tumor: Limited resection combined with neoadjuvant ALA-PDT |
| title_sort | advanced treatment of giant proliferating trichilemmal tumor limited resection combined with neoadjuvant ala pdt |
| topic | Proliferating trichilemmal tumor Neoadjuvant ALA-PDT Limited resection Photodynamic Therapy |
| url | http://www.sciencedirect.com/science/article/pii/S1572100023005975 |
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