Reliability and minimal detectable change of the MX3 hydration testing system.
Assessing hydration status outside of laboratories can be challenging given that most hydration measures are invasive, stationary, costly, or have questionable validity. This study investigated the within-day, test-retest reliability, and minimal detectable change (MDC) of the MX3 Hydration Testing...
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0313320 |
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| author | Ian Winter Josie Burdin Patrick B Wilson |
| author_facet | Ian Winter Josie Burdin Patrick B Wilson |
| author_sort | Ian Winter |
| collection | DOAJ |
| description | Assessing hydration status outside of laboratories can be challenging given that most hydration measures are invasive, stationary, costly, or have questionable validity. This study investigated the within-day, test-retest reliability, and minimal detectable change (MDC) of the MX3 Hydration Testing System (MX3 Diagnostics), a relatively low cost, noninvasive, and portable method to measure saliva osmolality. Seventy-five adults (44 men, 31 women; 29.6±10.8 yr, 171.1±9.2 cm, 79.1±15.4 kg) presented two saliva samples approximately 3 to 5 minutes apart. Fluid intake was avoided for at least 5 minutes prior to sample collections. For each sample collection, a researcher used the MX3 to tap the tip of a test strip to saliva on a participant's tongue. Intra-class correlation coefficients (ICCs) and MDC were calculated as measures of reliability. Means for the two measurements were 64.3±19.0 mOsm and 65.5±17.9 mOsm (mean difference of -1.2±13.0 mOsm; t = -0.806, p = 0.423). Further analysis with a two-one-sided test procedure revealed equivalence between the two SOSM measurements (p < 0.001 for upper and lower bounds). Within-day repeat measures yielded an ICC of 0.75 and an MDC at the 90% confidence level of 21.3 mOsm. With moderate-to-good reliability, the MX3 appears to be a practical choice for reliably measuring moderate-sized changes (>20 mOsm) in saliva osmolality outside of laboratory constraints. |
| format | Article |
| id | doaj-art-e12b5fded7984c468c356a1e3f731dba |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
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| spelling | doaj-art-e12b5fded7984c468c356a1e3f731dba2025-08-20T02:33:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-011911e031332010.1371/journal.pone.0313320Reliability and minimal detectable change of the MX3 hydration testing system.Ian WinterJosie BurdinPatrick B WilsonAssessing hydration status outside of laboratories can be challenging given that most hydration measures are invasive, stationary, costly, or have questionable validity. This study investigated the within-day, test-retest reliability, and minimal detectable change (MDC) of the MX3 Hydration Testing System (MX3 Diagnostics), a relatively low cost, noninvasive, and portable method to measure saliva osmolality. Seventy-five adults (44 men, 31 women; 29.6±10.8 yr, 171.1±9.2 cm, 79.1±15.4 kg) presented two saliva samples approximately 3 to 5 minutes apart. Fluid intake was avoided for at least 5 minutes prior to sample collections. For each sample collection, a researcher used the MX3 to tap the tip of a test strip to saliva on a participant's tongue. Intra-class correlation coefficients (ICCs) and MDC were calculated as measures of reliability. Means for the two measurements were 64.3±19.0 mOsm and 65.5±17.9 mOsm (mean difference of -1.2±13.0 mOsm; t = -0.806, p = 0.423). Further analysis with a two-one-sided test procedure revealed equivalence between the two SOSM measurements (p < 0.001 for upper and lower bounds). Within-day repeat measures yielded an ICC of 0.75 and an MDC at the 90% confidence level of 21.3 mOsm. With moderate-to-good reliability, the MX3 appears to be a practical choice for reliably measuring moderate-sized changes (>20 mOsm) in saliva osmolality outside of laboratory constraints.https://doi.org/10.1371/journal.pone.0313320 |
| spellingShingle | Ian Winter Josie Burdin Patrick B Wilson Reliability and minimal detectable change of the MX3 hydration testing system. PLoS ONE |
| title | Reliability and minimal detectable change of the MX3 hydration testing system. |
| title_full | Reliability and minimal detectable change of the MX3 hydration testing system. |
| title_fullStr | Reliability and minimal detectable change of the MX3 hydration testing system. |
| title_full_unstemmed | Reliability and minimal detectable change of the MX3 hydration testing system. |
| title_short | Reliability and minimal detectable change of the MX3 hydration testing system. |
| title_sort | reliability and minimal detectable change of the mx3 hydration testing system |
| url | https://doi.org/10.1371/journal.pone.0313320 |
| work_keys_str_mv | AT ianwinter reliabilityandminimaldetectablechangeofthemx3hydrationtestingsystem AT josieburdin reliabilityandminimaldetectablechangeofthemx3hydrationtestingsystem AT patrickbwilson reliabilityandminimaldetectablechangeofthemx3hydrationtestingsystem |