Insight on immune cells in rejection and infection postlung transplant
Abstract Objective The aim of this study is to provide a concise overview of the role of immune cells in rejection and infection after lung transplantation. Methods Based on previous clinical and basic studies, the role of various types of immune cells in the development of rejection and infection a...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-07-01
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| Series: | Immunity, Inflammation and Disease |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/iid3.868 |
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| _version_ | 1849253952640516096 |
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| author | Mingfeng Liao Chaoxi Wang Mingxia Zhang Kun Qiao |
| author_facet | Mingfeng Liao Chaoxi Wang Mingxia Zhang Kun Qiao |
| author_sort | Mingfeng Liao |
| collection | DOAJ |
| description | Abstract Objective The aim of this study is to provide a concise overview of the role of immune cells in rejection and infection after lung transplantation. Methods Based on previous clinical and basic studies, the role of various types of immune cells in the development of rejection and infection after lung transplantation is summarized. Results Immune cell functional status is strongly associated with common complications after lung transplantation, such as primary graft dysfunction, infection and occlusive bronchitis syndrome. Targeted balancing of immune cell tolerance and rejection is an important tool for successful lung transplantation. Conclusion A comprehensive understanding of immune cell function and the mechanisms that balance immune tolerance and immune rejection may be a crucial factor in improving survival after lung transplantation. |
| format | Article |
| id | doaj-art-e125126d094a4b82b5bb56633fddde45 |
| institution | Kabale University |
| issn | 2050-4527 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Immunity, Inflammation and Disease |
| spelling | doaj-art-e125126d094a4b82b5bb56633fddde452025-08-20T03:56:09ZengWileyImmunity, Inflammation and Disease2050-45272023-07-01117n/an/a10.1002/iid3.868Insight on immune cells in rejection and infection postlung transplantMingfeng Liao0Chaoxi Wang1Mingxia Zhang2Kun Qiao3Guangdong Key Lab for Diagnosis & Treatment of Emerging Infectious Diseases Shenzhen Third People's Hospital Shenzhen Guangdong Province People's Republic of ChinaDepartment of Thoracic Surgery Shenzhen Third People's Hospital Shenzhen Guangdong Province People's Republic of ChinaGuangdong Key Lab for Diagnosis & Treatment of Emerging Infectious Diseases Shenzhen Third People's Hospital Shenzhen Guangdong Province People's Republic of ChinaDepartment of Thoracic Surgery Shenzhen Third People's Hospital Shenzhen Guangdong Province People's Republic of ChinaAbstract Objective The aim of this study is to provide a concise overview of the role of immune cells in rejection and infection after lung transplantation. Methods Based on previous clinical and basic studies, the role of various types of immune cells in the development of rejection and infection after lung transplantation is summarized. Results Immune cell functional status is strongly associated with common complications after lung transplantation, such as primary graft dysfunction, infection and occlusive bronchitis syndrome. Targeted balancing of immune cell tolerance and rejection is an important tool for successful lung transplantation. Conclusion A comprehensive understanding of immune cell function and the mechanisms that balance immune tolerance and immune rejection may be a crucial factor in improving survival after lung transplantation.https://doi.org/10.1002/iid3.868immune cellslung transplantationobliterative bronchiolitisrejectiontolerance |
| spellingShingle | Mingfeng Liao Chaoxi Wang Mingxia Zhang Kun Qiao Insight on immune cells in rejection and infection postlung transplant Immunity, Inflammation and Disease immune cells lung transplantation obliterative bronchiolitis rejection tolerance |
| title | Insight on immune cells in rejection and infection postlung transplant |
| title_full | Insight on immune cells in rejection and infection postlung transplant |
| title_fullStr | Insight on immune cells in rejection and infection postlung transplant |
| title_full_unstemmed | Insight on immune cells in rejection and infection postlung transplant |
| title_short | Insight on immune cells in rejection and infection postlung transplant |
| title_sort | insight on immune cells in rejection and infection postlung transplant |
| topic | immune cells lung transplantation obliterative bronchiolitis rejection tolerance |
| url | https://doi.org/10.1002/iid3.868 |
| work_keys_str_mv | AT mingfengliao insightonimmunecellsinrejectionandinfectionpostlungtransplant AT chaoxiwang insightonimmunecellsinrejectionandinfectionpostlungtransplant AT mingxiazhang insightonimmunecellsinrejectionandinfectionpostlungtransplant AT kunqiao insightonimmunecellsinrejectionandinfectionpostlungtransplant |