Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocol
Introduction The human hand is extremely involved in our daily lives. However, the rehabilitation of hand function after stroke can be rather difficult due to the complexity of hand structure and function, as well as neural basis that supports hand function. Specifically, in individuals with moderat...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2019-09-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/9/9/e032413.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850220695531814912 |
|---|---|
| author | Li Ding Shugeng Chen Hewei Wang Jie Jia Ray Arceo Jun Yao |
| author_facet | Li Ding Shugeng Chen Hewei Wang Jie Jia Ray Arceo Jun Yao |
| author_sort | Li Ding |
| collection | DOAJ |
| description | Introduction The human hand is extremely involved in our daily lives. However, the rehabilitation of hand function after stroke can be rather difficult due to the complexity of hand structure and function, as well as neural basis that supports hand function. Specifically, in individuals with moderate to severe impairment following a stroke, previous evidence for effective treatments that recover hand function in this population is limited, and thus has never been reviewed. With the progress of rehabilitation science and tool development, results from more and more clinical trials are now available, thereby justifying conducting a systematic review.Methods and analysis This systematic review protocol is consistent with the methodology recommended by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols and the Cochrane handbook for systematic reviews of interventions. Electronic searches will be carried out in the PubMed, CINAHL, Physiotherapy Evidence Database and Cochrane Library databases, along with manual searches in the reference lists from included studies and published systematic reviews. The date range parameters used in searching all databases is between January 1999 and January 2019. Randomised controlled trials (RCTs) published in English, with the primary outcome focusing on hand motor function, will be included. Two reviewers will screen all retrieved titles, abstracts and full texts, perform the evaluation of the risk bias and extract all data independently. The risk of bias of the included RCTs will be evaluated by the Cochrane Collaboration’s tool. A qualitative synthesis will be provided in text and table, to summarise the main results of the selected publications. A meta-analysis will be considered if there is sufficient homogeneity across outcomes. The quality of the included publications will be evaluated by the Grading of Recommendations Assessment, Development and Evaluation system from the Cochrane Handbook for Systematic Reviews of Interventions.Ethics and dissemination No ethical approval is needed, and the results of this review will be disseminated via peer-reviewed publications and conference presentations.Trial registration number CRD42019128285. |
| format | Article |
| id | doaj-art-e122f551c40e452490f12a0ba9cbd00c |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2019-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-e122f551c40e452490f12a0ba9cbd00c2025-08-20T02:06:58ZengBMJ Publishing GroupBMJ Open2044-60552019-09-019910.1136/bmjopen-2019-032413Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocolLi Ding0Shugeng Chen1Hewei Wang2Jie Jia3Ray Arceo4Jun Yao5Beihang University, Beijing, China1 Department of Rehabilitation, Huashan Hospital, Fudan University, Shanghai, China2 Department of Rehabilitation, Huashan Hospital Fudan University, Shanghai, ChinaCARsgen Therapeutics Corp, Houston, Texas, USA2 Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois, USA4 Department of Respiratory and Critical Care Medicine,Guangyuan Central Hospital, Guangyuan, People`s Republic of ChinaIntroduction The human hand is extremely involved in our daily lives. However, the rehabilitation of hand function after stroke can be rather difficult due to the complexity of hand structure and function, as well as neural basis that supports hand function. Specifically, in individuals with moderate to severe impairment following a stroke, previous evidence for effective treatments that recover hand function in this population is limited, and thus has never been reviewed. With the progress of rehabilitation science and tool development, results from more and more clinical trials are now available, thereby justifying conducting a systematic review.Methods and analysis This systematic review protocol is consistent with the methodology recommended by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols and the Cochrane handbook for systematic reviews of interventions. Electronic searches will be carried out in the PubMed, CINAHL, Physiotherapy Evidence Database and Cochrane Library databases, along with manual searches in the reference lists from included studies and published systematic reviews. The date range parameters used in searching all databases is between January 1999 and January 2019. Randomised controlled trials (RCTs) published in English, with the primary outcome focusing on hand motor function, will be included. Two reviewers will screen all retrieved titles, abstracts and full texts, perform the evaluation of the risk bias and extract all data independently. The risk of bias of the included RCTs will be evaluated by the Cochrane Collaboration’s tool. A qualitative synthesis will be provided in text and table, to summarise the main results of the selected publications. A meta-analysis will be considered if there is sufficient homogeneity across outcomes. The quality of the included publications will be evaluated by the Grading of Recommendations Assessment, Development and Evaluation system from the Cochrane Handbook for Systematic Reviews of Interventions.Ethics and dissemination No ethical approval is needed, and the results of this review will be disseminated via peer-reviewed publications and conference presentations.Trial registration number CRD42019128285.https://bmjopen.bmj.com/content/9/9/e032413.full |
| spellingShingle | Li Ding Shugeng Chen Hewei Wang Jie Jia Ray Arceo Jun Yao Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocol BMJ Open |
| title | Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocol |
| title_full | Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocol |
| title_fullStr | Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocol |
| title_full_unstemmed | Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocol |
| title_short | Effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke: a systematic review protocol |
| title_sort | effectiveness of interventions to improve hand motor function in individuals with moderate to severe stroke a systematic review protocol |
| url | https://bmjopen.bmj.com/content/9/9/e032413.full |
| work_keys_str_mv | AT liding effectivenessofinterventionstoimprovehandmotorfunctioninindividualswithmoderatetoseverestrokeasystematicreviewprotocol AT shugengchen effectivenessofinterventionstoimprovehandmotorfunctioninindividualswithmoderatetoseverestrokeasystematicreviewprotocol AT heweiwang effectivenessofinterventionstoimprovehandmotorfunctioninindividualswithmoderatetoseverestrokeasystematicreviewprotocol AT jiejia effectivenessofinterventionstoimprovehandmotorfunctioninindividualswithmoderatetoseverestrokeasystematicreviewprotocol AT rayarceo effectivenessofinterventionstoimprovehandmotorfunctioninindividualswithmoderatetoseverestrokeasystematicreviewprotocol AT junyao effectivenessofinterventionstoimprovehandmotorfunctioninindividualswithmoderatetoseverestrokeasystematicreviewprotocol |