Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations
Abstract Given that lumbar disc herniation (LDH) is a prevalent spinal condition that causes significant individual suffering and societal costs, the genetic basis of LDH has received relatively little research. Our aim is to increase understanding of the genetic factors influencing LDH. We perform...
Saved in:
| Main Authors: | Ville Salo, Juhani Määttä, Eeva Sliz, FinnGen, Ene Reimann, Reedik Mägi, Estonian Biobank Research Team, Kadri Reis, Abdelrahman G. Elhanas, Anu Reigo, Priit Palta, Tõnu Esko, Jaro Karppinen, Johannes Kettunen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-53467-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pathway level metabolomics analysis identifies carbon metabolism as a key factor of incident hypertension in the Estonian Biobank
by: Liis Hiie, et al.
Published: (2025-03-01) -
Genome-wide association study of pulpal and apical diseases
by: Aino Salminen, et al.
Published: (2025-07-01) -
Plasma Metabolic Outliers Identified in Estonian Human Knockouts
by: Ketian Yu, et al.
Published: (2025-05-01) -
Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons.
by: Krista Fischer, et al.
Published: (2014-02-01) -
Effects of data transformation and model selection on feature importance in microbiome classification data
by: Zuzanna Karwowska, et al.
Published: (2025-01-01)