Recurrent Primary Intrasellar Paraganglioma
We describe a case of an 81-year-old male presenting with bitemporal visual field defects and blurry vision in the right eye. The patient was found to have a recurrent primary paraganglioma in the sellar and suprasellar region requiring a repeat transsphenoidal endoscopic resection. Immunohistochemi...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2020/2580160 |
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| _version_ | 1849467872447823872 |
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| author | Elizabeth A. Schueth Daniel C. Martinez Charles G. Kulwin Jose M. Bonnin Troy D. Payner Jonathan Y. Ting |
| author_facet | Elizabeth A. Schueth Daniel C. Martinez Charles G. Kulwin Jose M. Bonnin Troy D. Payner Jonathan Y. Ting |
| author_sort | Elizabeth A. Schueth |
| collection | DOAJ |
| description | We describe a case of an 81-year-old male presenting with bitemporal visual field defects and blurry vision in the right eye. The patient was found to have a recurrent primary paraganglioma in the sellar and suprasellar region requiring a repeat transsphenoidal endoscopic resection. Immunohistochemical examination confirmed paraganglioma with the classic zellballen appearance which stained positive for chromogranin, synaptophysin, and S-100 in the periphery. Paragangliomas (PGLs) in the sella turcica are a rare entity; only 19 cases have ever been reported in the literature. PGLs in the sellar region are often misdiagnosed or diagnosed in a delayed fashion. Earlier diagnosis of this locally aggressive tumor and meticulous debulking can prevent morbidity secondary to the tumor’s compressive effects. This report highlights the effectiveness of surgical interventions in treatment of paragangliomas. More research is still needed to determine the need for adjuvant therapies such as radiation. |
| format | Article |
| id | doaj-art-e11ee8704deb485cae04524e48770404 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-e11ee8704deb485cae04524e487704042025-08-20T03:26:00ZengWileyCase Reports in Otolaryngology2090-67652090-67732020-01-01202010.1155/2020/25801602580160Recurrent Primary Intrasellar ParagangliomaElizabeth A. Schueth0Daniel C. Martinez1Charles G. Kulwin2Jose M. Bonnin3Troy D. Payner4Jonathan Y. Ting5Indiana University School of Medicine, 1120 W. Michigan Street, Suite 200, Indianapolis, IN 46202, USADepartment of Otolaryngology – Head and Neck Surgery, Indiana University School of Medicine, 1130 W. Michigan Street, Fesler Hall, Suite 400, Indianapolis, IN 46202, USAGoodman Campbell Brain and Spine, 13345 Illinois Street, Carmel, IN 46032, USADepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, 350 W. 11th Street, Indiana University Health Pathology Laboratory, Indianapolis, IN 46202, USAGoodman Campbell Brain and Spine, 13345 Illinois Street, Carmel, IN 46032, USADepartment of Otolaryngology – Head and Neck Surgery, Indiana University School of Medicine, 1130 W. Michigan Street, Fesler Hall, Suite 400, Indianapolis, IN 46202, USAWe describe a case of an 81-year-old male presenting with bitemporal visual field defects and blurry vision in the right eye. The patient was found to have a recurrent primary paraganglioma in the sellar and suprasellar region requiring a repeat transsphenoidal endoscopic resection. Immunohistochemical examination confirmed paraganglioma with the classic zellballen appearance which stained positive for chromogranin, synaptophysin, and S-100 in the periphery. Paragangliomas (PGLs) in the sella turcica are a rare entity; only 19 cases have ever been reported in the literature. PGLs in the sellar region are often misdiagnosed or diagnosed in a delayed fashion. Earlier diagnosis of this locally aggressive tumor and meticulous debulking can prevent morbidity secondary to the tumor’s compressive effects. This report highlights the effectiveness of surgical interventions in treatment of paragangliomas. More research is still needed to determine the need for adjuvant therapies such as radiation.http://dx.doi.org/10.1155/2020/2580160 |
| spellingShingle | Elizabeth A. Schueth Daniel C. Martinez Charles G. Kulwin Jose M. Bonnin Troy D. Payner Jonathan Y. Ting Recurrent Primary Intrasellar Paraganglioma Case Reports in Otolaryngology |
| title | Recurrent Primary Intrasellar Paraganglioma |
| title_full | Recurrent Primary Intrasellar Paraganglioma |
| title_fullStr | Recurrent Primary Intrasellar Paraganglioma |
| title_full_unstemmed | Recurrent Primary Intrasellar Paraganglioma |
| title_short | Recurrent Primary Intrasellar Paraganglioma |
| title_sort | recurrent primary intrasellar paraganglioma |
| url | http://dx.doi.org/10.1155/2020/2580160 |
| work_keys_str_mv | AT elizabethaschueth recurrentprimaryintrasellarparaganglioma AT danielcmartinez recurrentprimaryintrasellarparaganglioma AT charlesgkulwin recurrentprimaryintrasellarparaganglioma AT josembonnin recurrentprimaryintrasellarparaganglioma AT troydpayner recurrentprimaryintrasellarparaganglioma AT jonathanyting recurrentprimaryintrasellarparaganglioma |