TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS

The objective of the research is to optimize the method of transnasal endoscopic plasty of liquor fistulas in patients with prolactinomas, who got nasal liquorrhea against the background of treatment with dopamine agonists.Material and methods. Transnasal endoscopic approach was performed in 7 cases...

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Main Authors: A. V. Polezhaev, V. Yu. Cherebillo, D. V. Svistov, U. A. Tsoy, D. V. Voitsekhovsky
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2018-06-01
Series:Вестник хирургии имени И.И. Грекова
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Online Access:https://www.vestnik-grekova.ru/jour/article/view/908
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author A. V. Polezhaev
V. Yu. Cherebillo
D. V. Svistov
U. A. Tsoy
D. V. Voitsekhovsky
author_facet A. V. Polezhaev
V. Yu. Cherebillo
D. V. Svistov
U. A. Tsoy
D. V. Voitsekhovsky
author_sort A. V. Polezhaev
collection DOAJ
description The objective of the research is to optimize the method of transnasal endoscopic plasty of liquor fistulas in patients with prolactinomas, who got nasal liquorrhea against the background of treatment with dopamine agonists.Material and methods. Transnasal endoscopic approach was performed in 7 cases with prolactinomas. There were 9 operations including 2 interventions caused by liquorrhea relapse. Plasty with Tachocomb and biological adhesives were used in 2 cases. The other 7 cases demanded additional use of an adipose tissue fragment.Results. Complete arrest of liquorrhea was achieved in 5 cases. It resumed in 2 patients who had undergone plasty with Tachcomb and biological adhesives. They needed into the reoperations with use of autoadipose tissue.Conclusion. Using of CTcisternography is necessary for revealing exact localization of liquor fistula. It is expedient to apply Tachocomb and a fragment of autoadipose tissue fixed with biological adhesives. Discontinuation of treatment with Cabergoline for a month is recommended after the operation.
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issn 0042-4625
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publishDate 2018-06-01
publisher Pavlov First Saint Petersburg State Medical University
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series Вестник хирургии имени И.И. Грекова
spelling doaj-art-e11ed4d11ec040a9af9310fe246cb9b82025-08-20T03:02:11ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252018-06-011773141810.24884/0042-4625-2018-177-3-14-18860TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGSA. V. Polezhaev0V. Yu. Cherebillo1D. V. Svistov2U. A. Tsoy3D. V. Voitsekhovsky4Federal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S. M. Kirov» of the Ministry of Defence of the Russian Federation; Federal State Budgetary Institution «Almazov National Medical Research Centre» of the Ministry of Health of the Russian FederationFederal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S. M. Kirov» of the Ministry of Defence of the Russian Federation; Federal State Budgetary Institution «Almazov National Medical Research Centre» of the Ministry of Health of the Russian FederationFederal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S. M. Kirov» of the Ministry of Defence of the Russian FederationFederal State Budgetary Institution «Almazov National Medical Research Centre» of the Ministry of Health of the Russian FederationFederal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S. M. Kirov» of the Ministry of Defence of the Russian FederationThe objective of the research is to optimize the method of transnasal endoscopic plasty of liquor fistulas in patients with prolactinomas, who got nasal liquorrhea against the background of treatment with dopamine agonists.Material and methods. Transnasal endoscopic approach was performed in 7 cases with prolactinomas. There were 9 operations including 2 interventions caused by liquorrhea relapse. Plasty with Tachocomb and biological adhesives were used in 2 cases. The other 7 cases demanded additional use of an adipose tissue fragment.Results. Complete arrest of liquorrhea was achieved in 5 cases. It resumed in 2 patients who had undergone plasty with Tachcomb and biological adhesives. They needed into the reoperations with use of autoadipose tissue.Conclusion. Using of CTcisternography is necessary for revealing exact localization of liquor fistula. It is expedient to apply Tachocomb and a fragment of autoadipose tissue fixed with biological adhesives. Discontinuation of treatment with Cabergoline for a month is recommended after the operation.https://www.vestnik-grekova.ru/jour/article/view/908prolactinomadopamine agonistscomplicationsnasal liquorrheatranssphenoidal surgeryplasty of liquor fistula
spellingShingle A. V. Polezhaev
V. Yu. Cherebillo
D. V. Svistov
U. A. Tsoy
D. V. Voitsekhovsky
TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS
Вестник хирургии имени И.И. Грекова
prolactinoma
dopamine agonists
complications
nasal liquorrhea
transsphenoidal surgery
plasty of liquor fistula
title TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS
title_full TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS
title_fullStr TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS
title_full_unstemmed TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS
title_short TRANSSPHENOIDAL SURGERY OF NASAL LIQUORRHEA AS A COMPLICATION AFTER TREATMENT OF PROLACTINOMAS WITH DRUGS
title_sort transsphenoidal surgery of nasal liquorrhea as a complication after treatment of prolactinomas with drugs
topic prolactinoma
dopamine agonists
complications
nasal liquorrhea
transsphenoidal surgery
plasty of liquor fistula
url https://www.vestnik-grekova.ru/jour/article/view/908
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AT dvsvistov transsphenoidalsurgeryofnasalliquorrheaasacomplicationaftertreatmentofprolactinomaswithdrugs
AT uatsoy transsphenoidalsurgeryofnasalliquorrheaasacomplicationaftertreatmentofprolactinomaswithdrugs
AT dvvoitsekhovsky transsphenoidalsurgeryofnasalliquorrheaasacomplicationaftertreatmentofprolactinomaswithdrugs