Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi

Objective. The aim of this study is to investigate urine fluoride concentration as a toxicity factor in a rural community in the state of San Luis Potosi, Mexico. Materials and Methods. A sample of 111 children exposed to high concentrations of fluoride in drinking water (4.13 mg/L) was evaluated. F...

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Main Authors: Lizet Jarquín-Yañez, José de Jesús Mejía-Saavedra, Nelly Molina-Frechero, Enrique Gaona, Diana Olivia Rocha-Amador, Olga Dania López-Guzmán, Ronell Bologna-Molina
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2015/647184
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author Lizet Jarquín-Yañez
José de Jesús Mejía-Saavedra
Nelly Molina-Frechero
Enrique Gaona
Diana Olivia Rocha-Amador
Olga Dania López-Guzmán
Ronell Bologna-Molina
author_facet Lizet Jarquín-Yañez
José de Jesús Mejía-Saavedra
Nelly Molina-Frechero
Enrique Gaona
Diana Olivia Rocha-Amador
Olga Dania López-Guzmán
Ronell Bologna-Molina
author_sort Lizet Jarquín-Yañez
collection DOAJ
description Objective. The aim of this study is to investigate urine fluoride concentration as a toxicity factor in a rural community in the state of San Luis Potosi, Mexico. Materials and Methods. A sample of 111 children exposed to high concentrations of fluoride in drinking water (4.13 mg/L) was evaluated. Fluoride exposure was determined by measuring urine fluoride concentration using the potentiometric method with an ion selective electrode. The diagnosis of dental fluorosis was performed by clinical examination, and the severity of damage was determined using Dean’s index and the Thylstrup-Fejerskov (TF) index. Results. The range of exposure in the study population, evaluated through the fluoride content in urine, was 1.1 to 5.9 mg/L, with a mean of 3.14 ± 1.09 mg/L. Dental fluorosis was present in all subjects, of which 95% had severe cases. Higher urine fluoride levels and greater degrees of severity occurred in older children. Conclusions. The results show that dental fluorosis was determined by the presence of fluoride exposure finding a high positive correlation between the severity of fluorosis and urine fluoride concentration and the years of exposure suggested a cumulative effect.
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spelling doaj-art-e1188b884d5c43babfbde755ca718d6f2025-08-20T02:21:28ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/647184647184Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis PotosiLizet Jarquín-Yañez0José de Jesús Mejía-Saavedra1Nelly Molina-Frechero2Enrique Gaona3Diana Olivia Rocha-Amador4Olga Dania López-Guzmán5Ronell Bologna-Molina6Center of Applied Research in Environment and Health, CIACYT, School of Medicine, Autonomous University of San Luis Potosi, 78100 San Luis Potosi, SLP, MexicoCenter of Applied Research in Environment and Health, CIACYT, School of Medicine, Autonomous University of San Luis Potosi, 78100 San Luis Potosi, SLP, MexicoDivision of Biological and Health Sciences, Metropolitan Autonomous University, 04960 Mexico City, MEX, MexicoDivision of Biological and Health Sciences, Metropolitan Autonomous University, 04960 Mexico City, MEX, MexicoDivision of Natural and Exact Sciences, University of Guanajuato, 36050 Guanajuato, GTO, MexicoSchool of Chemical Sciences, Durango Unit, Juarez University of the State of Durango, 3400 Durango, DGO, MexicoDepartment of Research, School of Dentistry, Juarez University of the State of Durango, 34000 Durango, DGO, MexicoObjective. The aim of this study is to investigate urine fluoride concentration as a toxicity factor in a rural community in the state of San Luis Potosi, Mexico. Materials and Methods. A sample of 111 children exposed to high concentrations of fluoride in drinking water (4.13 mg/L) was evaluated. Fluoride exposure was determined by measuring urine fluoride concentration using the potentiometric method with an ion selective electrode. The diagnosis of dental fluorosis was performed by clinical examination, and the severity of damage was determined using Dean’s index and the Thylstrup-Fejerskov (TF) index. Results. The range of exposure in the study population, evaluated through the fluoride content in urine, was 1.1 to 5.9 mg/L, with a mean of 3.14 ± 1.09 mg/L. Dental fluorosis was present in all subjects, of which 95% had severe cases. Higher urine fluoride levels and greater degrees of severity occurred in older children. Conclusions. The results show that dental fluorosis was determined by the presence of fluoride exposure finding a high positive correlation between the severity of fluorosis and urine fluoride concentration and the years of exposure suggested a cumulative effect.http://dx.doi.org/10.1155/2015/647184
spellingShingle Lizet Jarquín-Yañez
José de Jesús Mejía-Saavedra
Nelly Molina-Frechero
Enrique Gaona
Diana Olivia Rocha-Amador
Olga Dania López-Guzmán
Ronell Bologna-Molina
Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi
The Scientific World Journal
title Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi
title_full Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi
title_fullStr Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi
title_full_unstemmed Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi
title_short Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi
title_sort association between urine fluoride and dental fluorosis as a toxicity factor in a rural community in the state of san luis potosi
url http://dx.doi.org/10.1155/2015/647184
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