Cognitive Impairment in Opium Use Disorder
This cross-sectional study is aimed at assessing the effects of opium use disorder (OUD) on attention, working memory, and information-processing speed. Thirty outpatients with OUD and 20 healthy controls (HCs) were assessed using a neuropsychological battery consisted of Auditory Verbal Learning Te...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2021/5548623 |
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| _version_ | 1832549203048398848 |
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| author | Hossein Sanjari Moghaddam Behrang Shadloo Helen Shahkhah Abbas Tafakhori Maryam Haghshomar Shakila Meshkat Vajiheh Aghamollaii |
| author_facet | Hossein Sanjari Moghaddam Behrang Shadloo Helen Shahkhah Abbas Tafakhori Maryam Haghshomar Shakila Meshkat Vajiheh Aghamollaii |
| author_sort | Hossein Sanjari Moghaddam |
| collection | DOAJ |
| description | This cross-sectional study is aimed at assessing the effects of opium use disorder (OUD) on attention, working memory, and information-processing speed. Thirty outpatients with OUD and 20 healthy controls (HCs) were assessed using a neuropsychological battery consisted of Auditory Verbal Learning Test-Revised (AVLT-R), Brief Visuospatial Memory Test-Revised (BVMT-R), Digit Forward and Backward Tests (DFT and DBT), and WAIS-R Digit Symbol Substitution Test (DSST). The most affected cognitive functions in patients with OUD were detected by DBT and DSST. However, we found no significant difference between patients according to the route of administration. Within patients with OUD, DBT score was associated with opium use quantity (OUQ) (r=−0.385), and DBT (r=0.483) and DSST (r=0.542) scores were correlated with duration of use. Our findings indicated that working memory and information-processing speed are the most affected domains of cognitive functioning. DBT and DSST could be used as brief assessments in clinical settings to screen for cognitive deficits in patients with OUD. |
| format | Article |
| id | doaj-art-e110088084b6435fb7abf08085226a8b |
| institution | Kabale University |
| issn | 0953-4180 1875-8584 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-e110088084b6435fb7abf08085226a8b2025-02-03T06:12:00ZengWileyBehavioural Neurology0953-41801875-85842021-01-01202110.1155/2021/55486235548623Cognitive Impairment in Opium Use DisorderHossein Sanjari Moghaddam0Behrang Shadloo1Helen Shahkhah2Abbas Tafakhori3Maryam Haghshomar4Shakila Meshkat5Vajiheh Aghamollaii6School of Medicine, Tehran University of Medical Sciences, Tehran, IranIranian National Center for Addiction Studies (INCAS), Tehran University of Medical Sciences, Tehran, IranPsychiatry Department, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran, IranIranian Center of Neurological Research (ICNR), Tehran University of Medical Sciences, Tehran, IranSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranNeurology Department, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran, IranThis cross-sectional study is aimed at assessing the effects of opium use disorder (OUD) on attention, working memory, and information-processing speed. Thirty outpatients with OUD and 20 healthy controls (HCs) were assessed using a neuropsychological battery consisted of Auditory Verbal Learning Test-Revised (AVLT-R), Brief Visuospatial Memory Test-Revised (BVMT-R), Digit Forward and Backward Tests (DFT and DBT), and WAIS-R Digit Symbol Substitution Test (DSST). The most affected cognitive functions in patients with OUD were detected by DBT and DSST. However, we found no significant difference between patients according to the route of administration. Within patients with OUD, DBT score was associated with opium use quantity (OUQ) (r=−0.385), and DBT (r=0.483) and DSST (r=0.542) scores were correlated with duration of use. Our findings indicated that working memory and information-processing speed are the most affected domains of cognitive functioning. DBT and DSST could be used as brief assessments in clinical settings to screen for cognitive deficits in patients with OUD.http://dx.doi.org/10.1155/2021/5548623 |
| spellingShingle | Hossein Sanjari Moghaddam Behrang Shadloo Helen Shahkhah Abbas Tafakhori Maryam Haghshomar Shakila Meshkat Vajiheh Aghamollaii Cognitive Impairment in Opium Use Disorder Behavioural Neurology |
| title | Cognitive Impairment in Opium Use Disorder |
| title_full | Cognitive Impairment in Opium Use Disorder |
| title_fullStr | Cognitive Impairment in Opium Use Disorder |
| title_full_unstemmed | Cognitive Impairment in Opium Use Disorder |
| title_short | Cognitive Impairment in Opium Use Disorder |
| title_sort | cognitive impairment in opium use disorder |
| url | http://dx.doi.org/10.1155/2021/5548623 |
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