Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic waves

Background: The poor degradability of antibiotics in conventional wastewater treatment processes has recently encouraged researchers to use advanced oxidation processes based on persulfate (PS) activation. Therefore, the aim of our study was to remove ceftriaxone through the activation of persulfate...

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Main Authors: Zohreh Berizi, Mohammad Reza Zare, Leila rezaei, Ali Parvizimehr, salehe salehnia, Mohsen Rezaei, Nezamaddin Mengelizadeh
Format: Article
Language:fas
Published: Alborz University of Medical Sciences 2024-05-01
Series:Muhandisī-i Bihdāsht-i Muḥīṭ
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Online Access:http://jehe.abzums.ac.ir/article-1-843-en.pdf
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author Zohreh Berizi
Mohammad Reza Zare
Leila rezaei
Ali Parvizimehr
salehe salehnia
Mohsen Rezaei
Nezamaddin Mengelizadeh
author_facet Zohreh Berizi
Mohammad Reza Zare
Leila rezaei
Ali Parvizimehr
salehe salehnia
Mohsen Rezaei
Nezamaddin Mengelizadeh
author_sort Zohreh Berizi
collection DOAJ
description Background: The poor degradability of antibiotics in conventional wastewater treatment processes has recently encouraged researchers to use advanced oxidation processes based on persulfate (PS) activation. Therefore, the aim of our study was to remove ceftriaxone through the activation of persulfate with zero valence zinc/ultrasonic waves (Zn0/US). Methods: In this laboratory study, the sample containing the antibiotic ceftriaxone was subjected to persulfate activation through an ultrasonic probe with a frequency of 40 kHz. Optimization of operational parameters such as initial pH, catalyst dose, initial ceftriaxone concentration, reaction time and persulfate concentration was done through response surface methodology (RSM). In optimal conditions, synergistic effect, changes in wavelength scanning, mineralization rate and radical scavenger effect were studied. Finally, ceftriaxone concentration, chemical oxygen demand (COD) and total organic carbon (TOC) were measured through diagnostic devices. Results: Based on RSM analysis of variance, the maximum removal of antibiotic (94.54%), COD (66%) and TOC (54%) in laboratory conditions including pH equal to 3, 0.75 mg/L persulfate and catalyst concentration, 15 mg/L ceftriaxone and 45 minutes of reaction time were obtained. The presence of tert-butyl alcohol and ethanol as scavengers of hydroxyl and sulfate radicals decreased the efficiency rate of the process to 79% and 45% in the reaction time of 45 minutes and emphasized that the active species participate in ceftriaxone degradation. Conclusion: Based on the results, the process of Zn0/US/PS can be considered as a pretreatment process for the effective removal of ceftriaxone from water environments.
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spelling doaj-art-e10f1e761dd64e3188a2fcff887fc4672025-08-20T02:15:14ZfasAlborz University of Medical SciencesMuhandisī-i Bihdāsht-i Muḥīṭ2383-32112588-42392024-05-01113366379Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic wavesZohreh Berizi0Mohammad Reza Zare1Leila rezaei2Ali Parvizimehr3salehe salehnia4Mohsen Rezaei5Nezamaddin Mengelizadeh6 Department of Environmental Health Engineering, School of Health, Larestan University of Medical Sciences, Larestan, Iran Department of Environmental Health Engineering, School of Health, Larestan University of Medical Sciences, Larestan, Iran Department of Environmental Health Engineering, Emam reza hospital, Larestan university of medical Sciences, Larestan, Iran Department of Environmental Health Engineering, School of Health, Larestan University of Medical Sciences, Larestan, Iran Ferdows school of paramedical and health, Birjand University of Medical Sciences, Birjand, Iran Department of Environmental Health, Torbat Jam faculty of Medical Sciences, Torbat Jam, Iran Department of Environmental Health Engineering, School of Health, Larestan University of Medical Sciences, Larestan, Iran Background: The poor degradability of antibiotics in conventional wastewater treatment processes has recently encouraged researchers to use advanced oxidation processes based on persulfate (PS) activation. Therefore, the aim of our study was to remove ceftriaxone through the activation of persulfate with zero valence zinc/ultrasonic waves (Zn0/US). Methods: In this laboratory study, the sample containing the antibiotic ceftriaxone was subjected to persulfate activation through an ultrasonic probe with a frequency of 40 kHz. Optimization of operational parameters such as initial pH, catalyst dose, initial ceftriaxone concentration, reaction time and persulfate concentration was done through response surface methodology (RSM). In optimal conditions, synergistic effect, changes in wavelength scanning, mineralization rate and radical scavenger effect were studied. Finally, ceftriaxone concentration, chemical oxygen demand (COD) and total organic carbon (TOC) were measured through diagnostic devices. Results: Based on RSM analysis of variance, the maximum removal of antibiotic (94.54%), COD (66%) and TOC (54%) in laboratory conditions including pH equal to 3, 0.75 mg/L persulfate and catalyst concentration, 15 mg/L ceftriaxone and 45 minutes of reaction time were obtained. The presence of tert-butyl alcohol and ethanol as scavengers of hydroxyl and sulfate radicals decreased the efficiency rate of the process to 79% and 45% in the reaction time of 45 minutes and emphasized that the active species participate in ceftriaxone degradation. Conclusion: Based on the results, the process of Zn0/US/PS can be considered as a pretreatment process for the effective removal of ceftriaxone from water environments.http://jehe.abzums.ac.ir/article-1-843-en.pdfceftriaxonepersulfate activationresponse surface methodologymineralization rateoptimization
spellingShingle Zohreh Berizi
Mohammad Reza Zare
Leila rezaei
Ali Parvizimehr
salehe salehnia
Mohsen Rezaei
Nezamaddin Mengelizadeh
Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic waves
Muhandisī-i Bihdāsht-i Muḥīṭ
ceftriaxone
persulfate activation
response surface methodology
mineralization rate
optimization
title Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic waves
title_full Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic waves
title_fullStr Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic waves
title_full_unstemmed Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic waves
title_short Application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles/ultrasonic waves
title_sort application of response surface methodology in modeling and optimization of ceftriaxone decomposition with activated persulfate through zero valence zinc nanoparticles ultrasonic waves
topic ceftriaxone
persulfate activation
response surface methodology
mineralization rate
optimization
url http://jehe.abzums.ac.ir/article-1-843-en.pdf
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