Hemolytic uremic syndrome in children: a report of four cases with a literature review
Objective With a high fatality rate, hemolytic uremic syndrome（HUS）is one of the common causes of acute renal failure in children.The clinical characteristics and managements of pediatric HUS were summarized.Methods Clinical manifestations, auxiliary examinations, treatments and outcomes of 4 HUS ch...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2021-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57903861&Fpath=home&index=0 |
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| author | Xiao Shu-na Xia Zhi Cheng Ying Li Yong Shi Bu-yun Tang Wen Zhu Song-bai Qing Chengguang Xu Hui Huang Cheng-jiao |
| author_facet | Xiao Shu-na Xia Zhi Cheng Ying Li Yong Shi Bu-yun Tang Wen Zhu Song-bai Qing Chengguang Xu Hui Huang Cheng-jiao |
| author_sort | Xiao Shu-na |
| collection | DOAJ |
| description | Objective With a high fatality rate, hemolytic uremic syndrome（HUS）is one of the common causes of acute renal failure in children.The clinical characteristics and managements of pediatric HUS were summarized.Methods Clinical manifestations, auxiliary examinations, treatments and outcomes of 4 HUS children were retrospectively reviewed.Results After blood purification treatment, two children recovered well.One case recurred at Month 10 after discharge and regained health at Month 5 after readmission.One hospitalized child died after 68-day intermittent blood purification.Conclusions As a first-line option for HUS,plasma exchange may relieve the disease and improve its prognosis.It is the first-line treatment to HUS.Eculizumab is recommended for infants non-responding to plasma exchange. |
| format | Article |
| id | doaj-art-e10d9740abc448b0b6b9e9b081b4ddac |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2021-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-e10d9740abc448b0b6b9e9b081b4ddac2025-08-20T02:28:54ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-0126226557903861Hemolytic uremic syndrome in children: a report of four cases with a literature reviewXiao Shu-naXia ZhiCheng YingLi YongShi Bu-yunTang WenZhu Song-baiQing ChengguangXu HuiHuang Cheng-jiaoObjective With a high fatality rate, hemolytic uremic syndrome（HUS）is one of the common causes of acute renal failure in children.The clinical characteristics and managements of pediatric HUS were summarized.Methods Clinical manifestations, auxiliary examinations, treatments and outcomes of 4 HUS children were retrospectively reviewed.Results After blood purification treatment, two children recovered well.One case recurred at Month 10 after discharge and regained health at Month 5 after readmission.One hospitalized child died after 68-day intermittent blood purification.Conclusions As a first-line option for HUS,plasma exchange may relieve the disease and improve its prognosis.It is the first-line treatment to HUS.Eculizumab is recommended for infants non-responding to plasma exchange.http://www.lcszb.com/thesisDetails?columnId=57903861&Fpath=home&index=0Hemolytic uremic syndromeChildrenPlasma exchange |
| spellingShingle | Xiao Shu-na Xia Zhi Cheng Ying Li Yong Shi Bu-yun Tang Wen Zhu Song-bai Qing Chengguang Xu Hui Huang Cheng-jiao Hemolytic uremic syndrome in children: a report of four cases with a literature review Linchuang shenzangbing zazhi Hemolytic uremic syndrome Children Plasma exchange |
| title | Hemolytic uremic syndrome in children: a report of four cases with a literature review |
| title_full | Hemolytic uremic syndrome in children: a report of four cases with a literature review |
| title_fullStr | Hemolytic uremic syndrome in children: a report of four cases with a literature review |
| title_full_unstemmed | Hemolytic uremic syndrome in children: a report of four cases with a literature review |
| title_short | Hemolytic uremic syndrome in children: a report of four cases with a literature review |
| title_sort | hemolytic uremic syndrome in children a report of four cases with a literature review |
| topic | Hemolytic uremic syndrome Children Plasma exchange |
| url | http://www.lcszb.com/thesisDetails?columnId=57903861&Fpath=home&index=0 |
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