Pilon Fractures: An Ideal Model to Understand Biological Factors Implicated in the Pathogenesis of Posttraumatic Osteoarthritis

Pilon Fractures: An Ideal Model to Understand Biological Factors Implicated in the Pathogenesis of Posttraumatic Osteoarthritis

Category: Ankle Arthritis; Trauma Introduction/Purpose: Intraarticular pilon fractures have a high rate of posttraumatic osteoarthritis (PTOA) despite anatomic reduction of the articular surface. Elevated synovial inflammatory proteins triggered by injury contribute to PTOA development.MicroRNAs (mi...

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Main Authors: Jeffrey A. Foster MD, Jarod T. Griffin MD, Maaz Muhammad MD, Carlos R. Sierra-Arce MS, Wyatt G.S. Southall BS, Jacob S.W. Borgida BS, Robert K. Wagner MD, Ahmed Ismaeel PhD, John J. McCarthy PhD, Thuan V. Ly MD, Arjun Srinath MD, MPH, David C. Landy MD, PhD, Arun Aneja MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Foot & Ankle Orthopaedics
Online Access:https://doi.org/10.1177/2473011424S00432
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